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Multi-level ROS regulation to activate innate and adaptive immune therapies
Authors: Ke-Ke Feng, Cheng-Lei Li, Yi-Fan Tu, Shi-Cheng Tian, Rui Xiong, Bai-Sheng Sa, Jing-Wei Shao
Journal: Chemical Engineering Journal
Doi: doi.org/10.1016/j.cej.2025.163429
Products & Services: Gene Synthesis   
Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring
Authors: Xiangwei Wu, Huasong Ai, Junxiong Mao, Hongyi Cai, Lu-Jun Liang, Zebin Tong, Zhiheng Deng, Qingyun Zheng, Lei Liu, Man Pan
Journal: nature COMMUNICATION
PubMed ID: 40341121
Doi: doi.org/10.1038/s41467-025-59569-6
Fe(III)−H2O2 as an Alternative Oxidant for Catalytic Sulfoxidation in Cytochrome P450 Enzymes: Combined Theoretical and Experimental Evidence
Authors: Musen Li, Langxing Liao, Zhihui Jiang, Zongyu Bao, Shengbiao Ji, Binju Wang
Journal: ACS catalysis
Doi: doi.org/10.1021/acscatal.5c01673
Products & Services: Gene Synthesis   Codon Optimization   
Mechanistic insights into the stimulation of the histone H3K9 methyltransferase Clr4 by proximal H3K14 ubiquitination
Authors: Yunxiang Du , Maoshen Sun , Zhengqing Li , Xiangwei Wu , Qian Qu , Huasong Ai , Lei Liu
Journal: SCIENCE ADVANCES
PubMed ID: 40446033
Doi: 10.1126/sciadv.adu1864
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CRISPR-Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide-RNAs
Authors: Benjamín Durán-Vinet, Jo-Ann L. Stanton, Gert-Jan Jeunen, Ulla von Ammon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell
Journal: Environmental DNA
Doi: doi.org/10.1002/edn3.70105
An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element
Authors: Hengxia Jia, Shunli Liu, Guibo Rao, Qiaojie Liu, Jiqin Wu, Sheng Cao, Peng Gong
Journal: Sci Adv
PubMed ID: 40249801
Doi: 10.1126/sciadv.adv9640
Products & Services: Gene Synthesis   Custom Vector Construction   
Synergistic impact of macrolide resistance and H3N2 infection on M. pneumoniae outbreak in children
Authors: Jiali Chen, Yingdan Wang, Juan Cheng, Yunping Ma, Xin Zhang, Xuezhou Bai, Palizhati Rehati, Huashun Cui, Fan Wu, Qiuhui Pan, Jinghe Huang
Journal: Microbiology Spectrum
PubMed ID: 39998323
Doi: 10.1128/spectrum.01844-24
Products & Services: Gene Synthesis   
Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel
Authors: Young-Woo Nam, Dohyun Im, Ana Santa Cruz Garcia, Marios L Tringides, Hai Minh Nguyen, Yan Liu, Razan Orfali, Alena Ramanishka, Grigore Pintilie, Chih-Chia Su, Meng Cui, Diomedes E Logothetis, Edward W Yu, Heike Wulff, K George Chandy, Miao Zhang
Journal: Nat Commun
PubMed ID: 40246884
Doi: /10.1038/s41467-025-59061-1
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The structure and function of the ghrelin receptor coding for drug actions
Authors: Yuki Shiimura, Dohyun Im, Ryosuke Tany, Hidetsugu Asada, Ryoji Kise, Eon Kurumiya, Hideko Wakasugi-Masuho, Satoshi Yasuda, Kazuma Matsui, Jun-Ichi Kishikawa, Takayuki Kato, Takeshi Murata, Masayasu Kojima, So Iwata, Ikuo Masuho
Journal: Nat Struct Mol Biol
PubMed ID: 39833471
Doi: 39833471
Products & Services: Gene Synthesis   
Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide–HLA-I Fusion Protein by Armoring with Mutein IFNα
Authors: Douwe Freerk Samplonius , Anne Paulien van Wijngaarden , Lisanne Koll , Xiurong Ke , Wijnand Helfrich
Journal: Int J Mol Sci
PubMed ID: 40243928
Doi: ijms26073178
Products & Services: Gene Synthesis   
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