Uts2b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Uts2b
Entrez Gene ID	378939
Full Name	urotensin 2B
Synonyms	U2B,Urp,Uts2d
General protein information	Preferred Names urotensin 2B Names urotensin-2B U-IIB UIIB urotensin 2 domain containing urotensin II-related peptide urotensin IIB urotensin-2 domain-containing protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q22
Summary	binds urotensin II and produces hypotension [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_198133.2	NP_937766.1	urotensin-2B precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	UTS2B	NP_937795.2
Bos taurus (cattle)	UTS2B	XP_002684880.1
Macaca mulatta (Rhesus monkey)	UTS2D	XP_001094399.1
Pan troglodytes (chimpanzee)	UTS2D	XP_001161501.1
Mus musculus (house mouse)	Uts2b	NP_937809.1
Gallus gallus (chicken)	UTS2D	NP_996872.1
Rattus norvegicus (Norway rat)	Uts2b	NP_937766.1
Canis lupus familiaris (dog)	UTS2B	XP_850358.2
Xenopus tropicalis (tropical clawed frog)	uts2b	NP_001120467.1

Gene Ontology
Bibliography

Related articles in PubMed

Concordant localization of functional urotensin II and urotensin II-related peptide binding sites in the rat brain: Atypical occurrence close to the fourth ventricle.
Bucharles C, Bizet P, Arthaud S, Arabo A, Leprince J, Lefranc B, Cartier D, Anouar Y, Lihrmann I
The Journal of comparative neurology522(11)2634-49(2014 Aug)

Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart.
Doan ND, Nguyen TT, Létourneau M, Turcotte K, Fournier A, Chatenet D
British journal of pharmacology166(1)243-57(2012 May)

Direct evidence for the co-expression of URP and GnRH in a sub-population of rat hypothalamic neurones: anatomical and functional correlation.
Egginger JG, Parmentier C, Garrel G, Cohen-Tannoudji J, Camus A, Calas A, Hardin-Pouzet H, Grange-Messent V
PloS one6(10)e26611(2011)

Increased expression of urotensin II, urotensin II-related peptide and urotensin II receptor mRNAs in the cardiovascular organs of hypertensive rats: comparison with endothelin-1.
Hirose T, Takahashi K, Mori N, Nakayama T, Kikuya M, Ohkubo T, Kohzuki M, Totsune K, Imai Y
Peptides30(6)1124-9(2009 Jun)

Increased expression of urotensin II-related peptide and its receptor in kidney with hypertension or renal failure.
Mori N, Hirose T, Nakayama T, Ito O, Kanazawa M, Imai Y, Kohzuki M, Takahashi K, Totsune K
Peptides30(2)400-8(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Uts2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Uts2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04767	NM_198133.2 Latest version!	Rattus norvegicus urotensin 2B (Uts2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Uts2b ( NM_198133.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_937766.1 Rattus norvegicus urotensin 2B (Uts2b), mRNA.

Price & Availability↑

CloneID	ORa04767
Clone ID Related Accession (Same CDS sequence)	NM_198133.2
Accession Version	NM_198133.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1536854400000
Organism	Rattus norvegicus(Norway rat)
Product	urotensin-2B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY321314.1. On Oct 17, 2004 this sequence version replaced NM_198133.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY321314.1, AB116019.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689605, SAMN01906355 [ECO:0000350] ##Evidence-Data-END##

ATGAAGTTCT TCTCAACTTC TCTCTGCTTT GGACTCCTGG CTTTGTTGTC TGTGACGACC 
CTTTTACATT CTGTACGTGG ACGGCCGCAT CTGAGCTCAG GACATGAGTT ATTTCCAGCT 
GAAGAACACA CGACTCAGGA GAAACTACCG CTGGGTCTGC TGATCCGAAA CCCTGGTTTC 
CAGAGGCCCG CCCATGCTGG TGTAGATTTG CCCAGCAAAG TGGAAGAACT TAGACAGCTA 
AAGAAGCTGA GAGAATGGTT TATGGAGGCA AAGAGTGCTG AGCCGTCCAA TGCTTTAGAC 
AAGCTATCCT CTTCCCACCC TATTAAACGA GCTTGCTTTT GGAAATACTG TGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937766.1
CDS	63..419
Translation	MKFFSTSLCFGLLALLSVTTLLHSVRGRPHLSSGHELFPAEEHTTQEKLPLGLLIRNPGFQRPAHAGVDLPSKVEELRQLKKLREWFMEAKSAEPSNALDKLSSSHPIKRACFWKYCV

Target ORF information:

RefSeq Version	NM_198133.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus urotensin 2B (Uts2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198133.2

ORF Insert Sequence:

ATGAAGTTCT TCTCAACTTC TCTCTGCTTT GGACTCCTGG CTTTGTTGTC TGTGACGACC 
CTTTTACATT CTGTACGTGG ACGGCCGCAT CTGAGCTCAG GACATGAGTT ATTTCCAGCT 
GAAGAACACA CGACTCAGGA GAAACTACCG CTGGGTCTGC TGATCCGAAA CCCTGGTTTC 
CAGAGGCCCG CCCATGCTGG TGTAGATTTG CCCAGCAAAG TGGAAGAACT TAGACAGCTA 
AAGAAGCTGA GAGAATGGTT TATGGAGGCA AAGAGTGCTG AGCCGTCCAA TGCTTTAGAC 
AAGCTATCCT CTTCCCACCC TATTAAACGA GCTTGCTTTT GGAAATACTG TGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Concordant localization of functional urotensin II and urotensin II-related peptide binding sites in the rat brain: Atypical occurrence close to the fourth ventricle.
The Journal of comparative neurology522(11)2634-49(2014 Aug)
Bucharles C,Bizet P,Arthaud S,Arabo A,Leprince J,Lefranc B,Cartier D,Anouar Y,Lihrmann I

Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart.
British journal of pharmacology166(1)243-57(2012 May)
Doan ND,Nguyen TT,Létourneau M,Turcotte K,Fournier A,Chatenet D

Direct evidence for the co-expression of URP and GnRH in a sub-population of rat hypothalamic neurones: anatomical and functional correlation.
PloS one6(10)e26611(2011)
Egginger JG,Parmentier C,Garrel G,Cohen-Tannoudji J,Camus A,Calas A,Hardin-Pouzet H,Grange-Messent V

Increased expression of urotensin II, urotensin II-related peptide and urotensin II receptor mRNAs in the cardiovascular organs of hypertensive rats: comparison with endothelin-1.
Peptides30(6)1124-9(2009 Jun)
Hirose T,Takahashi K,Mori N,Nakayama T,Kikuya M,Ohkubo T,Kohzuki M,Totsune K,Imai Y

Increased expression of urotensin II-related peptide and its receptor in kidney with hypertension or renal failure.
Peptides30(2)400-8(2009 Feb)
Mori N,Hirose T,Nakayama T,Ito O,Kanazawa M,Imai Y,Kohzuki M,Takahashi K,Totsune K