Kdm2a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdm2a
Entrez Gene ID	361700
Full Name	lysine demethylase 2A
Synonyms	Fbxl11
General protein information	Preferred Names lysine demethylase 2A Names lysine-specific demethylase 2A F-box and leucine-rich repeat protein 11 lysine (K)-specific demethylase 2A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108515.1	NP_001101985.1	lysine-specific demethylase 2A
XM_006230844.3	XP_006230906.1	lysine-specific demethylase 2A isoform X1
XM_006230843.3	XP_006230905.1	lysine-specific demethylase 2A isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KDM2A	XP_865102.2
Bos taurus (cattle)	KDM2A	XP_002699409.2
Mus musculus (house mouse)	Kdm2a	NP_001001984.2
Rattus norvegicus (Norway rat)	Kdm2a	NP_001101985.1
Homo sapiens (human)	KDM2A	NP_036440.1
Danio rerio (zebrafish)	kdm2aa	NP_001075161.2
Macaca mulatta (Rhesus monkey)	KDM2A	XP_001107511.1
Gallus gallus (chicken)	KDM2A	XP_423678.3
Pan troglodytes (chimpanzee)	KDM2A	XP_001172828.1
Danio rerio (zebrafish)	kdm2a	XP_005173200.1
Drosophila melanogaster (fruit fly)	Kdm2	NP_001262400.1
Xenopus tropicalis (tropical clawed frog)	kdm2a	NP_001011176.1

Gene Ontology
Bibliography

Related articles in PubMed

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, Müller S, Oppermann U, Brennan PE
Cell chemical biology24(3)371-380(2017 Mar)

Fbxl11 Is a Novel Negative Element of the Mammalian Circadian Clock.
Reischl S, Kramer A
Journal of biological rhythms30(4)291-301(2015 Aug)

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.
Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N
Mechanisms of development13531-42(2015 Feb)

Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.
Dhar SS, Alam H, Li N, Wagner KW, Chung J, Ahn YW, Lee MG
The Journal of biological chemistry289(11)7483-96(2014 Mar)

Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.
Angrisano T, Schiattarella GG, Keller S, Pironti G, Florio E, Magliulo F, Bottino R, Pero R, Lembo F, Avvedimento EV, Esposito G, Trimarco B, Chiariotti L, Perrino C
PloS one9(9)e106024(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kdm2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdm2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07642	NM_001108515.1 Latest version!	Rattus norvegicus lysine demethylase 2A (Kdm2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa07642	XM_006230844.3 Latest version!	Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa07642	XM_006230843.3 Latest version!	Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdm2a ( NM_001108515.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101985.1 Rattus norvegicus lysine demethylase 2A (Kdm2a), mRNA.

Price & Availability↑

CloneID	ORa07642
Clone ID Related Accession (Same CDS sequence)	NM_001108515.1 , XM_006230844.3 , XM_006230843.3
Accession Version	NM_001108515.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1570636800000
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 2A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473953.1. On or before Oct 4, 2007 this sequence version replaced XM_341983.3, XM_001068749.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101985.1
CDS	388..3873
Translation	MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDMELNELESGNGDEEGADKEARRMNSKRSVLTSPVANGVNLDYDGLGKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSEKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS

Target ORF information:

RefSeq Version	NM_001108515.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 2A (Kdm2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108515.1

ORF Insert Sequence:

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm2a ( XM_006230844.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230906.1 Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa07642
Clone ID Related Accession (Same CDS sequence)	NM_001108515.1 , XM_006230844.3 , XM_006230843.3
Accession Version	XM_006230844.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 2A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230844.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230906.1
CDS	780..4265
Translation	MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDMELNELESGNGDEEGADKEARRMNSKRSVLTSPVANGVNLDYDGLGKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSEKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS

Target ORF information:

RefSeq Version	XM_006230844.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230844.3

ORF Insert Sequence:

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kdm2a ( XM_006230843.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230905.1 Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X1, mRNA.

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CloneID	ORa07642
Clone ID Related Accession (Same CDS sequence)	NM_001108515.1 , XM_006230844.3 , XM_006230843.3
Accession Version	XM_006230843.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1469376000000
Organism	Rattus norvegicus(Norway rat)
Product	lysine-specific demethylase 2A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230843.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230905.1
CDS	159..3644
Translation	MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDMELNELESGNGDEEGADKEARRMNSKRSVLTSPVANGVNLDYDGLGKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSEKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS

Target ORF information:

RefSeq Version	XM_006230843.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lysine demethylase 2A (Kdm2a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230843.3

ORF Insert Sequence:

ATGGAACCTG AAGAAGAAAG GATTCGGTAC AGCCAGAGAT TGCGTGGTAC CATGCGACGT 
CGCTATGAAG ATGATGGCAT TTCAGATGAT GAAATTGAAG GGAAAAGAAC TTTTGACTTG 
GAAGAGAAGC TCCATACCAA CAAATATAAT GCCAATTTTG TTACTTTTAT GGAGGGAAAA 
GATTTTAATG TAGAGTATAT CCAGCGGGGT GGCTTGAGAG ACCCTCTCAT TTTCAAGAAT 
TCTGATGGAC TTGGAATAAA GATGCCGGAT CCAGACTTCA CAGTGAATGA TGTCAAAATG 
TGTGTGGGGA GTCGTCGGAT GGTGGATGTC ATGGACGTGA ACACACAGAA GGGGATTGAA 
ATGACCATGG CGCAATGGAC ACGATACTAT GAGACTCCAG AGGAAGAGCG AGAGAAACTC 
TATAATGTTA TCAGCCTAGA GTTTAGCCAC ACCAGGCTTG AGAATATGGT ACAGCGGCCT 
TCCACGGTGG ATTTCATTGA CTGGGTAGAT AACATGTGGC CAAGGCACTT GAAAGAAAGT 
CAGACTGAAT CAACAAATGC CATCTTAGAG ATGCAGTACC CTAAAGTGCA AAAGTACTGT 
CTAATGAGTG TTCGAGGCTG CTATACTGAC TTCCATGTGG ATTTTGGAGG TACTTCTGTT 
TGGTATCACA TCCACCAAGG TGGAAAGGTC TTCTGGCTCA TCCCCCCTAC AGCCCACAAC 
CTGGAGCTGT ACGAGAATTG GCTGCTATCA GGGAAACAGG GAGACATCTT TCTGGGTGAC 
CGGGTGTCAG ATTGCCAACG AATTGAGCTC AAGCAGGGCT ATACCTTCGT TATTCCCTCA 
GGTTGGATTC ATGCTGTGTA TACTCCTACG GACACATTAG TGTTTGGAGG CAATTTTTTG 
CATAGCTTTA ACATCCCCAT GCAATTAAAG ATATATAGTA TTGAAGATCG AACACGGGTT 
CCAAATAAAT TCCGTTACCC ATTTTACTAT GAAATGTGTT GGTATGTGTT GGAGCGCTAT 
GTATACTGCA TAACCAACCG ATCTCACCTA ACTAAGGAAT TTCAGAAAGA ATCCCTTAGC 
ATGGATATGG AATTAAATGA GTTGGAGTCT GGAAATGGTG ATGAGGAAGG GGCGGACAAA 
GAAGCCCGAC GCATGAACAG TAAGCGATCT GTGCTTACCA GCCCTGTGGC TAATGGAGTC 
AACCTGGATT ATGATGGACT TGGCAAAGCC TGCCGAAGTC TTCCAAATCT GAAGAAAACT 
CTGTCTGGAG ACTCATCCTC AGACTCTAGT CGGGGATCCC ACAATGGCCA AGTTTGGGAT 
CCCCAATGTA GCCCTAGAAA GGATAGGCAA GTGCATCTGA CCCACTTTGA ACTTGAAGGT 
CTTCGATGTC TTGTAGATAA GTTAGAGTCA CTGCCACTGC ACAAGAAGTG TGTCCCCACA 
GGGATAGAAG ACGAAGATGC TCTGATTGCT GATGTAAAGA TTTTGCTGGA AGAACTTGCC 
AGTAGTGATC CCAAGTTAGC CCTCACTGGA GTTCCCATAG TACAGTGGCC AAAAAGGGAT 
AAGCTTAAAT TTCCGACCAG GCCAAAGGTG AGGGTTCCTA CAATTCCCAT CACAAAGCCT 
CACACCATGA AGCCGGCTCC GCGCCTAACA CCTGTAAGGC CTGCTGCAGC CTCCCCCATT 
GTGTCAGGAG CCAGGCGGAG AAGAGTGCGC TGCAGGAAAT GCAAAGCCTG TGTGCAAGGA 
GAATGTGGAG TCTGCCACTA CTGCAGGGAC ATGAAGAAAT TTGGTGGGCC TGGACGCATG 
AAGCAGTCCT GTGTCCTCAG ACAGTGCTTA GCACCTAGAC TGCCTCATTC AGTTACATGT 
TCTCTCTGTG GAGAAGTAGA TCAGAATGAA GAGACACAGG ACTTTGAAAA GAAACTCATG 
GAATGCTGCA TCTGCAACGA GATAGTTCAT CCTGGCTGCC TCCAGATGGA TGGAGAGGGG 
TTGCTTAACG AGGAATTGCC AAATTGCTGG GAGTGTCCAA AGTGTTATCA GGAAGACAGC 
TCGGAGAAAG CCCAGAAGCG GAAAATAGAA GAGAGTGATG AAGAAGCTGT ACAAGCCAAA 
GTCCTACGGC CCCTGAGGAG CTGCGAGGAG CCTCTCACAC CCCCGCCTCA CTCACCTACT 
TCCATGCTGC AGCTCATCCA CGACCCGGTT TCTCCCCGGG GTATGGTGAC TCGGTCATCC 
CCTGGGGCTG GCCCCAGCGA CCACCACAGT GCCAGCCGTG ATGAACGCTT CAAACGGCGG 
CAGTTGCTGC GGCTACAAGC CACAGAGCGC ACCATGGTAC GGGAAAAGGA GAACAATCCC 
AGCGGCAAAA AGGAGCTGTC TGAAGTTGAG AAAGCCAAGA TCCGGGGATC GTACCTCACT 
GTCACGCTAC AGAGGCCCAC CAAAGAGCTC CACGGGACAT CCATTGTGCC CAAGCTGCAG 
GCCATCACGG CCTCCTCTGC CAACCTTCGC CCTAACCCCC GTGTGCTAAT GCAGCACTGC 
CCAGCCCGGA ACCCCCAGCG TGGGGATGAG GAGGGGCTTG GGGGAGAGGA GGAGGAAGAG 
GAGGAGGAGG AGGAAGATGA CAGTGCAGAG GAGGGGGGTG CAGCAAGGCT GAATGGCCGG 
GGCAGTTGGG CTCAGGATGG AGACGAAAGC TGGATGCAGC GGGAGGTCTG GATGTCTGTC 
TTCCGCTACC TCAGCCGCAG AGAACTTTGT GAATGTATGC GAGTGTGCAA GACGTGGTAT 
AAATGGTGCT GTGACAAACG ACTTTGGACA AAAATTGACT TGAGTAGGTG TAAGGCCATC 
GTGCCCCAGG CTCTCAGTGG CATCATCAAG CGGCAGCCAG TAAGCCTGGA CCTTAGTTGG 
ACTAACATCT CCAAAAAGCA GCTGACATGG CTGGTCAATA GGCTGCCAGG ATTAAAAGAC 
CTCCTCCTAG CAGGCTGTTC CTGGTCTGCA GTATCTGCCC TCAGCACCTC CAGCTGCCCC 
CTTCTCAGGA CCCTTGATCT TCGGTGGGCA GTAGGAATTA AAGACCCTCA AATTCGGGAC 
TTGCTGACTC CACCCACAGA TAAGCCAGGT CAAGACAATC GAAGCAAACT CCGGAACATG 
ACTGACTTCC GGCTGGCAGG CCTTGACATC ACCGATGCCA CTCTCCGACT CATTATTCGC 
CACATGCCCC TTTTGTCTCG ACTTGACCTC AGTCACTGCA GCCACCTTAC AGATCAGTCC 
TCCAACCTGC TCACTGCTGT CGGGTCTTCC ACTCGATACT CCCTTACAGA GCTCAACATG 
GCGGGTTGCA ATAAACTGAC AGACCAGACC CTGTTCTTCC TAAGGAGAAT TGCTAATGTC 
ACCTTGATTG ACCTTCGAGG ATGCAAACAG ATCACAAGAA AAGCCTGTGA GCACTTCATC 
TCAGACTTGT CCATCAACAG CCTCTACTGC CTGTCTGATG AGAAACTGAT ACAGAAGATT 
AGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Cell chemical biology24(3)371-380(2017 Mar)
Tumber A,Nuzzi A,Hookway ES,Hatch SB,Velupillai S,Johansson C,Kawamura A,Savitsky P,Yapp C,Szykowska A,Wu N,Bountra C,Strain-Damerell C,Burgess-Brown NA,Ruda GF,Fedorov O,Munro S,England KS,Nowak RP,Schofield CJ,La Thangue NB,Pawlyn C,Davies F,Morgan G,Athanasou N,Müller S,Oppermann U,Brennan PE

Fbxl11 Is a Novel Negative Element of the Mammalian Circadian Clock.
Journal of biological rhythms30(4)291-301(2015 Aug)
Reischl S,Kramer A

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.
Mechanisms of development13531-42(2015 Feb)
Kawakami E,Tokunaga A,Ozawa M,Sakamoto R,Yoshida N

Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells.
The Journal of biological chemistry289(11)7483-96(2014 Mar)
Dhar SS,Alam H,Li N,Wagner KW,Chung J,Ahn YW,Lee MG

Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.
PloS one9(9)e106024(2014)
Angrisano T,Schiattarella GG,Keller S,Pironti G,Florio E,Magliulo F,Bottino R,Pero R,Lembo F,Avvedimento EV,Esposito G,Trimarco B,Chiariotti L,Perrino C

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Kdm2a cDNA ORF clone, Rattus norvegicus(Norway rat)

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