MFAP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MFAP2
Entrez Gene ID	4237
Full Name	microfibril associated protein 2
Synonyms	MAGP,MAGP-1,MAGP1
General protein information	Preferred Names microfibril associated protein 2 Names microfibrillar-associated protein 2 microfibril-associated glycoprotein 1 microfibrillar associated protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.13
Summary	Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Disorder MIM:	156790

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135248.1	NP_001128720.1	microfibrillar-associated protein 2 isoform b precursor
NM_002403.3	NP_002394.1	microfibrillar-associated protein 2 isoform a precursor
NM_002403.4	NP_002394.1	microfibrillar-associated protein 2 isoform a precursor
NM_001135247.1	NP_001128719.1	microfibrillar-associated protein 2 isoform b precursor
XM_011541476.2	XP_011539778.1	microfibrillar-associated protein 2 isoform X1
NM_017459.2	NP_059453.1	microfibrillar-associated protein 2 isoform a precursor

Pathways from BioSystems

Homologies

Macaca mulatta (Rhesus monkey)	MFAP2	XP_002802247.1
Bos taurus (cattle)	MFAP2	NP_776813.1
Danio rerio (zebrafish)	mfap2	NP_001034446.1
Xenopus tropicalis (tropical clawed frog)	mfap2	NP_989000.1
Gallus gallus (chicken)	MFAP2	XP_003642560.2
Rattus norvegicus (Norway rat)	Mfap2	NP_001101459.1
Homo sapiens (human)	MFAP2	NP_002394.1
Pan troglodytes (chimpanzee)	MFAP2	XP_001154988.1
Canis lupus familiaris (dog)	MFAP2	XP_544541.2
Mus musculus (house mouse)	Mfap2	NP_001155271.1

Gene Ontology
Bibliography

Related articles in PubMed

Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease.
Craft CS, Broekelmann TJ, Mecham RP
Matrix biology : journal of the International Society for Matrix Biology71-72100-111(2018 10)

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Naba A, Pearce OMT, Del Rosario A, Ma D, Ding H, Rajeeve V, Cutillas PR, Balkwill FR, Hynes RO
Journal of proteome research16(8)3083-3091(2017 08)

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Ragelle H, Naba A, Larson BL, Zhou F, Prijić M, Whittaker CA, Del Rosario A, Langer R, Hynes RO, Anderson DG
Biomaterials128147-159(2017 06)

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L
Human molecular genetics24(6)1791-800(2015 Mar)

Human eye development is characterized by coordinated expression of fibrillin isoforms.
Hubmacher D, Reinhardt DP, Plesec T, Schenke-Layland K, Apte SS
Investigative ophthalmology & visual science55(12)7934-44(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MFAP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MFAP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17929	XM_011541476.2 Latest version!	Homo sapiens microfibrillar associated protein 2 (MFAP2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26197	NM_001135247.1 Latest version!	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu26197	NM_001135248.1 Latest version!	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu17929	NM_002403.4 Latest version!	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
OHu17929	NM_017459.2 Latest version!	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
View Old Accession Versions >>
OHu17929	NM_002403.3	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MFAP2 ( XM_011541476.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011539778.1 Homo sapiens microfibrillar associated protein 2 (MFAP2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17929
Clone ID Related Accession (Same CDS sequence)	NM_002403.3 , NM_002403.4 , XM_011541476.2 , NM_017459.2
Accession Version	XM_011541476.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541476.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011539778.1
CDS	741..1292
Translation	MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	XM_011541476.2
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibrillar associated protein 2 (MFAP2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541476.2

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MFAP2 ( NM_001135248.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128720.1 Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu26197
Clone ID Related Accession (Same CDS sequence)	NM_001135248.1 , NM_001135247.1
Accession Version	NM_001135248.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC015039.1, AK222751.1 and BC028033.1. Transcript Variant: This variant (4) uses an alternate in-frame splice site compared to variant 2. The resulting isoform (b) has the same N- and C-termini but is one aa shorter compared to isoform a. Variants 3 and 4 both encode isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222751.1, AL553496.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGGCT TGCTGGCTCA GGGCCAGTAT 
GACCTGGACC CGCTGCCGCC GTTCCCTGAC CACGTCCAGT ACACCCACTA TAGCGACCAG 
ATCGACAACC CAGACTACTA TGATTATCAA GAGGTGACTC CTCGGCCCTC CGAGGAACAG 
TTCCAGTTCC AGTCCCAGCA GCAAGTCCAA CAGGAAGTCA TCCCAGCCCC AACCCCAGAA 
CCAGGAAATG CAGAGCTGGA GCCCACAGAG CCTGGGCCTC TTGACTGCCG TGAGGAACAG 
TACCCGTGCA CCCGCCTCTA CTCCATACAC AGGCCTTGCA AACAGTGTCT CAACGAGGTC 
TGCTTCTACA GCCTCCGCCG TGTGTACGTC ATTAACAAGG AGATCTGTGT TCGTACAGTG 
TGTGCCCATG AGGAGCTCCT CCGAGCTGAC CTCTGTCGGG ACAAGTTCTC CAAATGTGGC 
GTGATGGCCA GCAGCGGCCT GTGCCAATCC GTGGCGGCCT CCTGTGCCAG GAGCTGTGGG 
AGCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128720.1
CDS	134..682
Translation	MRAAYLFLLFLPGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	NM_001135248.1
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135248.1

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGGCT TGCTGGCTCA GGGCCAGTAT 
GACCTGGACC CGCTGCCGCC GTTCCCTGAC CACGTCCAGT ACACCCACTA TAGCGACCAG 
ATCGACAACC CAGACTACTA TGATTATCAA GAGGTGACTC CTCGGCCCTC CGAGGAACAG 
TTCCAGTTCC AGTCCCAGCA GCAAGTCCAA CAGGAAGTCA TCCCAGCCCC AACCCCAGAA 
CCAGGAAATG CAGAGCTGGA GCCCACAGAG CCTGGGCCTC TTGACTGCCG TGAGGAACAG 
TACCCGTGCA CCCGCCTCTA CTCCATACAC AGGCCTTGCA AACAGTGTCT CAACGAGGTC 
TGCTTCTACA GCCTCCGCCG TGTGTACGTC ATTAACAAGG AGATCTGTGT TCGTACAGTG 
TGTGCCCATG AGGAGCTCCT CCGAGCTGAC CTCTGTCGGG ACAAGTTCTC CAAATGTGGC 
GTGATGGCCA GCAGCGGCCT GTGCCAATCC GTGGCGGCCT CCTGTGCCAG GAGCTGTGGG 
AGCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MFAP2 ( NM_001135247.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128719.1 Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu26197
Clone ID Related Accession (Same CDS sequence)	NM_001135248.1 , NM_001135247.1
Accession Version	NM_001135247.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577030400000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU280150.1, AK222751.1 and BC028033.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site and differs in the 5' UTR compared to variant 2. The resulting isoform (b) has the same N- and C-termini but is one aa shorter compared to isoform a. Variants 3 and 4 both encode isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK222751.1, AL553496.3 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGGCT TGCTGGCTCA GGGCCAGTAT 
GACCTGGACC CGCTGCCGCC GTTCCCTGAC CACGTCCAGT ACACCCACTA TAGCGACCAG 
ATCGACAACC CAGACTACTA TGATTATCAA GAGGTGACTC CTCGGCCCTC CGAGGAACAG 
TTCCAGTTCC AGTCCCAGCA GCAAGTCCAA CAGGAAGTCA TCCCAGCCCC AACCCCAGAA 
CCAGGAAATG CAGAGCTGGA GCCCACAGAG CCTGGGCCTC TTGACTGCCG TGAGGAACAG 
TACCCGTGCA CCCGCCTCTA CTCCATACAC AGGCCTTGCA AACAGTGTCT CAACGAGGTC 
TGCTTCTACA GCCTCCGCCG TGTGTACGTC ATTAACAAGG AGATCTGTGT TCGTACAGTG 
TGTGCCCATG AGGAGCTCCT CCGAGCTGAC CTCTGTCGGG ACAAGTTCTC CAAATGTGGC 
GTGATGGCCA GCAGCGGCCT GTGCCAATCC GTGGCGGCCT CCTGTGCCAG GAGCTGTGGG 
AGCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128719.1
CDS	115..663
Translation	MRAAYLFLLFLPGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	NM_001135247.1
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135247.1

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGGCT TGCTGGCTCA GGGCCAGTAT 
GACCTGGACC CGCTGCCGCC GTTCCCTGAC CACGTCCAGT ACACCCACTA TAGCGACCAG 
ATCGACAACC CAGACTACTA TGATTATCAA GAGGTGACTC CTCGGCCCTC CGAGGAACAG 
TTCCAGTTCC AGTCCCAGCA GCAAGTCCAA CAGGAAGTCA TCCCAGCCCC AACCCCAGAA 
CCAGGAAATG CAGAGCTGGA GCCCACAGAG CCTGGGCCTC TTGACTGCCG TGAGGAACAG 
TACCCGTGCA CCCGCCTCTA CTCCATACAC AGGCCTTGCA AACAGTGTCT CAACGAGGTC 
TGCTTCTACA GCCTCCGCCG TGTGTACGTC ATTAACAAGG AGATCTGTGT TCGTACAGTG 
TGTGCCCATG AGGAGCTCCT CCGAGCTGAC CTCTGTCGGG ACAAGTTCTC CAAATGTGGC 
GTGATGGCCA GCAGCGGCCT GTGCCAATCC GTGGCGGCCT CCTGTGCCAG GAGCTGTGGG 
AGCTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MFAP2 ( NM_002403.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002394.1 Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17929
Clone ID Related Accession (Same CDS sequence)	NM_002403.3 , NM_002403.4 , XM_011541476.2 , NM_017459.2
Accession Version	NM_002403.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1549036800000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC015039.1, DN996554.1 and BC028033.1. On Sep 27, 2008 this sequence version replaced NM_002403.2. Transcript Variant: This variant (2) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015039.1, ERR279858.1207.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002394.1
CDS	134..685
Translation	MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	NM_002403.3
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002403.3

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MFAP2 ( NM_002403.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002394.1 Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17929
Clone ID Related Accession (Same CDS sequence)	NM_002403.3 , NM_002403.4 , XM_011541476.2 , NM_017459.2
Accession Version	NM_002403.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1571500800000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DN996554.1 and BC028033.1. On May 17, 2019 this sequence version replaced NM_002403.3. Transcript Variant: This variant (2) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.588010.1, SRR7346977.206278.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375535.4/ ENSP00000364685.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002394.1
CDS	76..627
Translation	MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	NM_002403.4
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002403.4

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MFAP2 ( NM_017459.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_059453.1 Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 1, mRNA.

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CloneID	OHu17929
Clone ID Related Accession (Same CDS sequence)	NM_002403.3 , NM_002403.4 , XM_011541476.2 , NM_017459.2
Accession Version	NM_017459.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Homo sapiens(human)
Product	microfibrillar-associated protein 2 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AU280150.1, AK222751.1 and BC028033.1. This sequence is a reference standard in the RefSeqGene project. On or before Nov 2, 2012 this sequence version replaced XM_003960903.1, XM_003960904.1, XM_003960905.1, NM_017459.1. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CN428584.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059453.1
CDS	115..666
Translation	MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Target ORF information:

RefSeq Version	NM_017459.2
Organism	Homo sapiens(human)
Definition	Homo sapiens microfibril associated protein 2 (MFAP2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017459.2

ORF Insert Sequence:

ATGAGAGCTG CCTACCTCTT CCTGCTATTC CTGCCTGCAG GCTTGCTGGC TCAGGGCCAG 
TATGACCTGG ACCCGCTGCC GCCGTTCCCT GACCACGTCC AGTACACCCA CTATAGCGAC 
CAGATCGACA ACCCAGACTA CTATGATTAT CAAGAGGTGA CTCCTCGGCC CTCCGAGGAA 
CAGTTCCAGT TCCAGTCCCA GCAGCAAGTC CAACAGGAAG TCATCCCAGC CCCAACCCCA 
GAACCAGGAA ATGCAGAGCT GGAGCCCACA GAGCCTGGGC CTCTTGACTG CCGTGAGGAA 
CAGTACCCGT GCACCCGCCT CTACTCCATA CACAGGCCTT GCAAACAGTG TCTCAACGAG 
GTCTGCTTCT ACAGCCTCCG CCGTGTGTAC GTCATTAACA AGGAGATCTG TGTTCGTACA 
GTGTGTGCCC ATGAGGAGCT CCTCCGAGCT GACCTCTGTC GGGACAAGTT CTCCAAATGT 
GGCGTGATGG CCAGCAGCGG CCTGTGCCAA TCCGTGGCGG CCTCCTGTGC CAGGAGCTGT 
GGGAGCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease.
Matrix biology : journal of the International Society for Matrix Biology71-72100-111(2018 10)
Craft CS,Broekelmann TJ,Mecham RP

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Journal of proteome research16(8)3083-3091(2017 08)
Naba A,Pearce OMT,Del Rosario A,Ma D,Ding H,Rajeeve V,Cutillas PR,Balkwill FR,Hynes RO

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Biomaterials128147-159(2017 06)
Ragelle H,Naba A,Larson BL,Zhou F,Prijić M,Whittaker CA,Del Rosario A,Langer R,Hynes RO,Anderson DG

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
Human molecular genetics24(6)1791-800(2015 Mar)
He M,Xu M,Zhang B,Liang J,Chen P,Lee JY,Johnson TA,Li H,Yang X,Dai J,Liang L,Gui L,Qi Q,Huang J,Li Y,Adair LS,Aung T,Cai Q,Cheng CY,Cho MC,Cho YS,Chu M,Cui B,Gao YT,Go MJ,Gu D,Gu W,Guo H,Hao Y,Hong J,Hu Z,Hu Y,Huang J,Hwang JY,Ikram MK,Jin G,Kang DH,Khor CC,Kim BJ,Kim HT,Kubo M,Lee J,Lee J,Lee NR,Li R,Li J,Liu J,Longe J,Lu W,Lu X,Miao X,Okada Y,Ong RT,Qiu G,Seielstad M,Sim X,Song H,Takeuchi F,Tanaka T,Taylor PR,Wang L,Wang W,Wang Y,Wu C,Wu Y,Xiang YB,Yamamoto K,Yang H,Liao M,Yokota M,Young T,Zhang X,Kato N,Wang QK,Zheng W,Hu FB,Lin D,Shen H,Teo YY,Mo Z,Wong TY,Lin X,Mohlke KL,Ning G,Tsunoda T,Han BG,Shu XO,Tai ES,Wu T,Qi L

Human eye development is characterized by coordinated expression of fibrillin isoforms.
Investigative ophthalmology & visual science55(12)7934-44(2014 Nov)
Hubmacher D,Reinhardt DP,Plesec T,Schenke-Layland K,Apte SS

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MFAP2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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