CRISPR News

Learn about CRISPR/Cas9-based non-viral knockin for T cell engineering and how the Marson lab at UCSF is optimizing these methods to support T cell therapies.

Learn about advances using CRISPR/Cas13 nucleases in viral detection and treatment, including influenza A and SARS-CoV-2.

Learn how long stranded DNA (lssDNA) donor templates facilitates knockin CRISPR/Cas9 editing efficiency for animal model generation.

Learn how CRISPR/Cas9 gene-editing ex vivo and in vivo approaches are progressing to treat beta-thalassemia, sickle cell disease, Leber congenital amaurosis, and hereditary transthyretin amyloidosis.

Novel CRISPR-based Non-viral Approach for CAR T Cell Generation

Overcoming Antibiotic Resistance with CRISPR

Learn about strategies to improve the efficiency of CRISPR mediated knock-in of donor DNA templates.

CRISPR/Cas9 Used to Edit Gene Variance in Human Stem cell-derived β cells from a Patient with Monogenic Diabetes and Reverse Preexisting Diabetes in Mice

Learn about Jennifer Doudna and Emmanuelle Charpentier, the 2020 Nobel prize-Chemistry recipients, for elucidating CRISPR/Cas9’s mechanisms in bacterial immunity as well as its potential for genome editing applications.

Learn about CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/Cas delivery and how viral vs non-viral approaches compare.