CRISPR/Cas9 Therapeutic Applications

Both well-established pharmaceutical companies and new start-up biotech companies are racing to create CRISPR-based therapeutics. Compared to other strategies for gene therapy, CRISPR genome editing is thought to be faster, less expensive, and potentially far safer. Autologous CRISPR cell therapies that use genome editing to correct a mutation in a patient’s own cells hold promise in circumventing the rejection issues present with transplant therapies that require donor matching. CRISPR genome editing is especially promising for diseases that can be tackled by modifying cells that can easily be removed from a patient, which allows for additional screening to ensure no off-target genome modifications during genome-editing.

CRISPR Services

CRISPR gRNA Plasmids

Licensed from the Feng Zhang Laboratory at the Broad Institute

Learn More

CRISPR
sgRNA

A powerful tool for creating gene knock-ins and knock-outs

Learn More

HDR Knock-in Templates

ssDNA and dsDNA HDR donor templates for effective gene knock-in

Learn More

CRISPR Cell Lines

Genetically modified cell line in any mammalian cell line and targeting any gene.

Learn More

Microbial Gene Editing

Highly efficient, seamless genome editing in E.coli using CRISPR technology

Learn More

CRISPR gRNA Libraries

Genome-wide gRNA libraries for efficient screening

Learn More