Applications

Create synthetic gene variants

Develop gene therapies

Create epigenetic modifications for regulation of gene expression

Gene rearrangement

Problems

Genetic deletions and insertions are responsible for an array of genetic disorders. Deletion of any number of base pairs not evenly divisible by three leads to frameshift mutations, which render all subsequent codons unreadable. These produce severely altered and often nonfunctional proteins. For this reason, gene variants play an increasingly important role in research into the relationship between geneotype and phenotype. However, the most useful gene variants, particularly gene mutants and rearranged genes, can be difficult to obtain by PCR amplification and many other methods. Gene synthesis has become an indispensable tool.

Our Solution

GenScript has developed its own proprietary gene synthesis technologies, including means of synthesizing gene mutants and rearranged genes. This technology is based on advances in the understanding of gene synthesis, of the relationship between gene structure and function, and of geneotype and phenotype. With an extensive history of speedy and reliable gene synthesis, GenScript can help you design your own high-quality genes and cDNAs at highly competitive prices. GenScript guarantees DNA deletion, insertion or rearrangement at the specific target site.

Our Advantages

Let GenScript's vast experience in gene mutant synthesis and custom gene synthesis accelerate your research by providing you with high-quality genes specifically mutated for your application or research.

Quotations and Ordering

  • For quotation requests and questions, you may contact us by email, phone, or via our secured online quotation system.
  • Orders can be placed by phone, email, fax, or online with a formal PO (Purchase Order) or credit card.

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The products and services in this section are for Research Use Only. Not for use in human clinical diagnostics or therapeutics or in vitro diagnostic procedures.

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