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AMG 925 is a dual FLT3/CDK4 inhibitor with the potential to overcome FLT3 inhibitor resistance in acute myeloid leukemia.
Authors: Li C, Liu L, Liang L, Xia Z, Li Z, Wang X, McGee LR, Newhall K, Sinclair A, Kamb A, Wickramasinghe D, Dai K.
Journal: Mol Cancer Ther.
PubMed ID: 25487917
Combinatorial active-site variants confer sustained clavulanate resistance in BlaC β-lactamase from Mycobacterium tuberculosis.
Authors: P Egesborg, H Carlettini, JP Volpato, N Doucet.
Journal: Protein Sci.
PubMed ID: 25492589
Generation in yeast of recombinant virus-like particles of porcine circovirus type 2 capsid protein and their use for a serologic assay and development of monoclonal antibodies.
Authors: Nainys J, Lasickiene R, Petraityte-Burneikiene R, Dabrisius J, Lelesius R, Sereika V, Zvirbliene A, Sasnauskas K, Gedvilaite A.
Journal: BMC Biotechnol. 14(1):100
PubMed ID: 25487652
A+-Helix of protein C inhibitor (PCI) is a cell-penetrating peptide, which mediates cell membrane permeation of PCI.
Authors: H Yang, FC Wahlmueller, B Sarg, M Furtmueller, Geiger M.
Journal: J Biol Chem.
PubMed ID: 25488662
Mesenchymal properties of SJL mice-stem cells and their efficacy as autologous therapy in relapsing-remitting multiple sclerosis model.
Authors: Marin-Bañasco C, SuardÍaz GarcÍa M, Hurtado Guerrero I, Maldonado SÁnchez R, Estivill-TorrÚs G, Leyva FernÁndez L, FernÁndez FernÁndez O.
Journal: Stem Cell Res Ther.
PubMed ID: 25498031
BcRISP1, isolated from non-heading Chinese cabbage, decreases the seed set of transgenic Arabidopsis
Authors: T Liu, Y Qian, W Duan, J Ren, X Hou, Y Li.
Journal: Horticulture research.
Phosphorylation of Glucocorticoid Receptor tau1c Transactivation Domain Enhances Binding to CREB Binding Protein (CBP) TAZ2.
Authors: CW Carruthers, JH Suh, JA Gustafsson, P Webb.
Journal: Biochem Biophys Res Commun.
PubMed ID: 25511704
Development of an improved vaccine evaluation protocol to compare the efficacy of Newcastle disease vaccines.
Authors: Cardenas-Garcia S, Diel DG, Susta L, Lucio-Decanini E, Yu Q, Brown CC, Miller PJ, Afonso CL.
Journal: Biologicals.
PubMed ID: 25511007
Gene Conversion between Cationic Trypsinogen (PRSS1) and the Pseudogene Trypsinogen 6 (PRSS3P2) in Patients with Chronic Pancreatitis.
Authors: Rygiel AM, Beer S, Simon P, Wertheim-Tysarowska K, Oracz G, Kucharzik T, Tysarowski A, NiepokÓj K, Kierkus J, Jurek M, Gawli??ski P, Pozna??ski J, Bal J, Lerch MM, Sahin-TÓth M, Weiss FU.
Journal: Hum Mutat.
PubMed ID: 25546417
Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes - A homogenous system for sequence-specific detection.
Authors: Howard RL, French DJ, Richardson JA, O'Neill CE, Andreou MP, Brown T, Clark D, Clarke IN, Holloway JW, Marsh P, Debenham PG.
Journal: Mol Cell Probes.
PubMed ID: 25542839
Rapid and Sensitive Detection of Bartonella bacilliformis in Experimentally Infected Sand Flies by Loop-Mediated Isothermal Amplification (LAMP) of the Pap31 Gene.
Authors: Angkasekwinai N, Atkins EH, Johnson RN, Grieco JP, Ching WM, Chao CC.
Journal: PLoS Negl Trop Dis. 8(12):e3342
PubMed ID: 25522230
Effects of CHO-expressed recombinant lactoferrins on mouse dendritic cell presentation and function.
Authors: Hwang SA, Kruzel ML, Actor JK.
Journal: Innate Immun.
PubMed ID: 25537452
Stable expression of a bifunctional diterpene synthase in the chloroplast of Chlamydomonas reinhardtii.
Authors: J A Z Zedler, D Gangl, B Hamberger, S Purton, C Robinson.
Journal: J Appl Phycol.
A natural genetic variant of granzyme B confers lethality to a common viral infection.
Authors: Andoniou CE, Sutton VR, Wikstrom ME, Fleming P, Thia KY, Matthews AY, Kaiserman D, Schuster IS, Coudert JD, Eldi P, Chaudhri G, Karupiah G, Bird PI, Trapani JA, Degli-Esposti MA.
Journal: PLoS Pathog. 10(12):e1004526
PubMed ID: 25502180
Characterization of the Aggregates Formed by Various Bacterial Lipopolysaccharides in Solution and upon Interaction with Antimicrobial Peptides.
Authors: Bello G, Eriksson J, Terry A, Edwards K, Lawrence MJ, Barlow D, Harvey RD.
Journal: Langmuir.
PubMed ID: 25514503
Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD.
Authors: Davis E, Chen J, Leon K, Darst SA, Campbell EA.
Journal: Nucleic Acids Res. 43(1):433-45
PubMed ID: 25510492
Molecular cloning and characterization of a novel bovine IFN-ε
Authors: Guo Y, Gao M, Bao J, Luo X, Liu Y, An D, Zhang H, Ma B, Wang J.
Journal: Gene.
PubMed ID: 25523095
The A6V polymorphism of the human μ-opioid receptor negatively impacts signalling of morphine and endogenous opioids in vitro.
Authors: Knapman A, Santiago M, Connor M.
Journal: Br J Pharmacol.
PubMed ID: 25521224
Astakine LvAST binds to the β subunit of F1-ATP synthase and likely plays a role in white shrimp Litopeneaus vannamei defense against white spot syndrome virus.
Authors: Liang GF, Liang Y, Xue Q, Lu JF, Cheng JJ, Huang J.
Journal: Fish Shellfish Immunol. 43(1):75-81
PubMed ID: 25536411
New NOBOX Mutations identified in a Large Cohort of Women with Primary Ovarian Insufficiency decrease KIT-L Expression.
Authors: Bouilly J, Roucher-Boulez F, Gompel A, Bry-Gauillard H, Azibi K, Beldjord C, DodÉ C, Bouligand J, Guiochon Mantel A, HÉcart AC, Delemer B, Young J, Binart N.
Journal: J Clin Endocrinol Metab.
PubMed ID: 25514101
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