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48 Results

Confronting the Challenges of Solid Tumors with Antigen Spreading

Learn how pre-existent immunity against non-tumor targets may be leveraged to drive immune cells towards the tumor microenvironment resulting in antigen spreading and reduced tumor growth.

Jul 24, 2022

Achieving Efficient Therapeutic Genome Editing in Mammalian Cells with Cas12i

Researchers from Arbor Biotechnologies have developed a versatile, specific, and high-efficiency genome-editing platform and showed the therapeutic potential of Cas12i in mammalian cells for the first time.

Jul 16, 2022

Lighting the Way to Antibody Drugs against Human Metapneumovirus

From human memory B cells, researchers at Merck & Co. have recently isolated over a hundred monoclonal antibodies that specifically target human metapneumovirus, a common cause of acute lower respiratory infection in children.

Jun 15, 2022

CAR (NAP) T Cell, An Armed CAR T Cell Revolutionizing Cancer Immunotherapy

Researchers at Uppsala University have recently developed novel CAR T cells that outcompete conventional ones and induce advantageous immunological responses against solid tumors in mouse models.

May 14, 2022

Perturb-map, A New Technology Cracking Tumor Microenvironment Mystery

Perturb-map is a new spatial functional genomics technology that unravels the mystery of tumor microenvironment and speeds up the discovery of new targets for better cancer therapies.

May 08, 2022

SEAKER, A New Type of CAR T Cell for Better Cancer Treatment

Researchers from Sloan Kettering Cancer Center recently designed a new type of CAR T cell that overcomes many hurdles of regular CAR T cell therapy and greatly enhances the anti-tumor efficacy of genetically engineered T cells.

Mar 17, 2022

Evaluating SARS-CoV-2 Immune Memory in a Golden Hamster Model

Learn how investigators leverage the golden hamster model system to understand adaptive immune memory responses to SARS-CoV-2 and VOC.

Jan 15, 2022

Researchers Found New “Eyes” of Immune System to Detect Cancer Cells

Researchers from Oslo University Hospital recently found an appealing cancer target named TdT for short, providing new "eyes" of immune system to detect cancer cells.

Jan 04, 2022

Research Digest