ORF » Species Summary » Canis lupus familiaris » Reactome

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Canis lupus familiaris (dog)

Browse by Letter Index, Genomic Locus


Vitamin D (calciferol) metabolism Branched-chain amino acid catabolism
Carnitine synthesis Phenylalanine and tyrosine catabolism
Tryptophan catabolism Methionine salvage pathway
Amine-derived hormones Thyroxine biosynthesis
Selenoamino acid metabolism Xenobiotics
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Miscellaneous substrates
FMO oxidises nucleophiles Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Glucuronidation Aflatoxin activation and detoxification
Abacavir transport and metabolism Abacavir metabolism
Reversible hydration of carbon dioxide Mitochondrial translation elongation
Cargo trafficking to the periciliary membrane Trafficking of myristoylated proteins to the cilium
Base Excision Repair Depurination
Resolution of Abasic Sites (AP sites) Resolution of AP sites via the single-nucleotide replacement pathway
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH Translesion synthesis by POLK
DNA Double-Strand Break Repair Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
HDR through Homologous Recombination (HRR) Nucleotide Excision Repair
DNA Damage Recognition in GG-NER Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER ABC transporters in lipid homeostasis
Transport of inorganic cations/anions and amino acids/oligopeptides Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Facilitative Na+-independent glucose transporters Inositol transporters
Zinc efflux and compartmentalization by the SLC30 family Na+/Cl- dependent neurotransmitter transporters
Vasopressin regulates renal water homeostasis via Aquaporins Ligand-gated ion channel transport
Regulation of Hypoxia-inducible Factor (HIF) by oxygen Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oncogene Induced Senescence DNA Damage/Telomere Stress Induced Senescence
Autodegradation of the E3 ubiquitin ligase COP1 G2/M Checkpoints
G2/M DNA damage checkpoint Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Inactivation of APC/C via direct inhibition of the APC/C complex Activation of the pre-replicative complex
Orc1 removal from chromatin Unwinding of DNA
Establishment of Sister Chromatid Cohesion Loss of Nlp from mitotic centrosomes
M Phase Golgi Cisternae Pericentriolar Stack Reorganization
Clearance of Nuclear Envelope Membranes from Chromatin Mitotic Prometaphase
Assembly of the pre-replicative complex Phosphorylation of Emi1
Phosphorylation of the APC/C Nucleosome assembly
Removal of the Flap Intermediate from the C-strand Generation of second messenger molecules
CD28 co-stimulation PD-1 signaling
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers AKT phosphorylates targets in the cytosol
Class I MHC mediated antigen processing & presentation Cross-presentation of soluble exogenous antigens (endosomes)
Trafficking and processing of endosomal TLR TAK1 activates NFkB by phosphorylation and activation of IKKs complex
MAP3K8 (TPL2)-dependent MAPK1/3 activation ERK/MAPK targets
Toll Like Receptor 5 (TLR5) Cascade MyD88 dependent cascade initiated on endosome
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Complement cascade
TRAF3-dependent IRF activation pathway TRAF6 mediated NF-kB activation
Defensins STING mediated induction of host immune responses
Role of phospholipids in phagocytosis RAF activation
Negative regulation of MAPK pathway Negative feedback regulation of MAPK pathway
PKA activation C-type lectin receptors (CLRs)
CLEC7A/inflammasome pathway Interferon Signaling
Interferon alpha/beta signaling Interleukin receptor SHC signaling
IL-6-type cytokine receptor ligand interactions Interleukin-7 signaling
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