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Canis lupus familiaris (dog)


Nuclear Pore Complex (NPC) Disassembly Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
APC/C:Cdc20 mediated degradation of mitotic proteins APC-Cdc20 mediated degradation of Nek2A
APC/C:Cdc20 mediated degradation of Cyclin B APC/C:Cdc20 mediated degradation of Securin
Telomere Maintenance Processive synthesis on the C-strand of the telomere
Immune System Adaptive Immune System
Downstream TCR signaling PIP3 activates AKT signaling
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling CD22 mediated BCR regulation
IRAK2 mediated activation of TAK1 complex JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
MAPK targets/ Nuclear events mediated by MAP kinases CREB phosphorylation
Activation of the AP-1 family of transcription factors Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor 9 (TLR9) Cascade Creation of C4 and C2 activators
Lectin pathway of complement activation Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Inflammasomes The NLRP3 inflammasome
Advanced glycosylation endproduct receptor signaling Cytosolic sensors of pathogen-associated DNA
ZBP1(DAI) mediated induction of type I IFNs LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
Fcgamma receptor (FCGR) dependent phagocytosis DAP12 interactions
RAF/MAP kinase cascade MAP2K and MAPK activation
Fc epsilon receptor (FCERI) signaling Cytokine Signaling in Immune system
Interferon gamma signaling Interleukin-1 processing
Interleukin-3, 5 and GM-CSF signaling Interleukin-6 family signaling
NIK-->noncanonical NF-kB signaling NCAM signaling for neurite out-growth
Netrin-1 signaling Signaling by Robo receptor
RNA Polymerase III Transcription Processing of Capped Intronless Pre-mRNA
mRNA Editing: A to I Conversion C6 deamination of adenosine
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
Epigenetic regulation of gene expression RNA polymerase II transcribes snRNA genes
Non-integrin membrane-ECM interactions Syndecan interactions
MET receptor recycling Keratinization
Synthesis of active ubiquitin: roles of E1 and E2 enzymes FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Regulation of TLR by endogenous ligand Ub-specific processing proteases
RET signaling TFAP2 (AP-2) family regulates transcription of cell cycle factors
Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Reversal of alkylation damage by DNA dioxygenases Glycogen synthesis
Fructose metabolism Lactose synthesis
Keratan sulfate degradation HS-GAG biosynthesis
Chondroitin sulfate/dermatan sulfate metabolism Dermatan sulfate biosynthesis
Trafficking of dietary sterols Fatty acid, triacylglycerol, and ketone body metabolism
Mitochondrial Fatty Acid Beta-Oxidation Synthesis of Ketone Bodies
Cholesterol biosynthesis Regulation of cholesterol biosynthesis by SREBP (SREBF)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol Estrogen biosynthesis
Choline catabolism PI and PC transport between ER and Golgi membranes
Hydrolysis of LPC Acyl chain remodelling of PS
Synthesis of PIPs at the early endosome membrane alpha-linolenic acid (ALA) metabolism
Synthesis of 5-eicosatetraenoic acids Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Sphingolipid metabolism
NOSIP mediated eNOS trafficking Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Citric acid cycle (TCA cycle) The proton buffering model
Purine ribonucleoside monophosphate biosynthesis Pyrimidine salvage reactions
Metabolism of vitamins and cofactors Metabolism of water-soluble vitamins and cofactors
Vitamins B6 activation to pyridoxal phosphate Nicotinamide salvaging
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