Webinars » Anti-idiotype Antibody: Generation and application in therapeutic antibody development
Anti-idiotype antibodies (anti-IDs) recognize the idiotype; paratope binding region, of another antibody, usually an antibody drug. This makes them incredibly useful in pharmacokinetic (PK) and pharmacodynamic (PD) studies to specifically measure circulating antibody drug concentrations during pre-clinical and clinical studies. In addition, the resemblance of anti-IDs to anti-drug antibodies(ADAs) makes them perfect positive control or reference standards in immunogenicity assays.
Principal Project Manager of GenScript’s Project Management Center
SDr. Li Chen is in charge of the therapeutic antibody discovery service platform at GenScript USA Inc. Dr. Chen received his Ph.D. from the University of Massachusetts Medical School, specializing in immunology and bioinformatics. Dr. Chen has extensive experience in Antibody drug discovery, including publication of three patents in antibody discovery field.
Specializing in Multi-Immunization Lead Generation
Fully integrated platform from antigen design to IND filing
High throughput screening for lead generation and optimization
Solution to problematic antigens, such as transmembrane proteins and intracellular domains
Proven track record with 100% success rate
High specificity & affinity from rabbit based anti-ID generation services
Mouse anti-ID generation services ideal for PK analysis
Fast turnaround time: 2-3 months
100% success rate
Picomolar Level KD Values for Exceptional Affinity
Antigen to Antibody in as little as 4 months
Combining hybridoma and recombinant technologies to generate high yields of natural purified antibodies