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pcDNA3.1(-)_myc-His B ✎

It is designed for high-level protein expression in mammalian cells

Backbone Information

  • Vector Type: Mammalian Expression Vector
  • Expression system: Mammalian
  • Bacterial Resistance(s): Ampicillin
  • Copy number: High

Component Information

  • Promoter1: CMV promoter
  • Enhancer1: CMV enhancer
  • Promoter2: T7
  • Tag: XXXXX
  • Selection marker: XXXXX
  • P2A/IRES: XXXXX

Reference

  • Cappella M, Ciotti C, Cohen-Tannoudji M, Biferi MG. Gene Therapy for ALS-A Perspective. Int J Mol Sci. 2019 Sep 6;20(18):4388. Cappella M, Ciotti C, Cohen-Tannoudji M, Biferi MG. Gene Therapy for ALS-A Perspective. Int J Mol Sci. 2019 Sep 6;20(18):4388.
  • ALS.org (n.d.). Therapies Targeting ALS-Linked Genetic Mutations | The ALS Association. The ALS Association. Retrieved May 22, 2024
  • Ling JP, Pletnikova O, Troncoso JC, Wong PC. TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD. Science.