Hapln4 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hapln4
Entrez Gene ID	330790
Full Name	hyaluronan and proteoglycan link protein 4
Synonyms	9330174O11,Bral2,Lpr4
General protein information	Preferred Names hyaluronan and proteoglycan link protein 4 Names hyaluronan and proteoglycan link protein 4 brain link protein 2 brain linked protein 2 link protein 4
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 8 Map Location: 8\|8 B3.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_177900.4	NP_808568.1	hyaluronan and proteoglycan link protein 4 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	HAPLN4	NP_075378.1
Macaca mulatta (Rhesus monkey)	LOC719748	XP_001115139.1
Bos taurus (cattle)	HAPLN4	XP_002688581.3
Rattus norvegicus (Norway rat)	Hapln4	NP_001101868.1
Rattus norvegicus (Norway rat)	LOC100911378	XP_003751617.2
Pan troglodytes (chimpanzee)	HAPLN4	XP_524163.2
Xenopus tropicalis (tropical clawed frog)	hapln4	XP_002936377.1
Mus musculus (house mouse)	Hapln4	NP_808568.1
Danio rerio (zebrafish)	hapln4	NP_001038372.1
Canis lupus familiaris (dog)	HAPLN4	XP_005632715.1
Gallus gallus (chicken)	HAPLN4	XP_003642936.1

Gene Ontology
Bibliography

Related articles in PubMed

Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons.
Edamatsu M, Miyano R, Fujikawa A, Fujii F, Hori T, Sakaba T, Oohashi T
Journal of neurochemistry147(6)748-763(2018 12)

A deficiency of the link protein Bral2 affects the size of the extracellular space in the thalamus of aged mice.
Cicanic M, Edamatsu M, Bekku Y, Vorisek I, Oohashi T, Vargova L
Journal of neuroscience research96(2)313-327(2018 02)

The absence of brain-specific link protein Bral2 in perineuronal nets hampers auditory temporal resolution and neural adaptation in mice.
Popelář J, Díaz Gómez M, Lindovský J, Rybalko N, Burianová J, Oohashi T, Syka J
Physiological research66(5)867-880(2017 11)

Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum.
Bekku Y, Saito M, Moser M, Fuchigami M, Maehara A, Nakayama M, Kusachi S, Ninomiya Y, Oohashi T
The Journal of comparative neurology520(8)1721-36(2012 Jun)

The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.
Schilling K, Oberdick J
Cerebellum (London, England)8(4)477-89(2009 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hapln4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hapln4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu07005	NM_177900.4 Latest version!	Mus musculus hyaluronan and proteoglycan link protein 4 (Hapln4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hapln4 ( NM_177900.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_808568.1 Mus musculus hyaluronan and proteoglycan link protein 4 (Hapln4), mRNA.

Price & Availability↑

CloneID	OMu07005
Clone ID Related Accession (Same CDS sequence)	NM_177900.4
Accession Version	NM_177900.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1203bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577376000000
Organism	Mus musculus(house mouse)
Product	hyaluronan and proteoglycan link protein 4 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC167132.12. On Nov 17, 2006 this sequence version replaced NM_177900.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AB107882.1, SRR1660813.75595.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849376 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTGTG CTCCAGGAGC CCTCGGTCAC CGCGCACTCT GGGCCGTGGC CTGGGGACTC 
CTGCTGCTGG TCCCCGTGCT CGCAGGGGCG CAGCGTGGCA GGAAGAAAGT CGTGCACGTG 
CTGGAGGGCG AGTCCGGTTC CGTGGTGGTG CAGACGGCGC CGGGGCAGGT GGTGAGCCAC 
CGCGGTGGTA CCATTGTCTT ACCCTGCCGT TACCACTACG AGGCGGCCGC CCACGGTCAC 
GACGGCGTCC GCCTCAAGTG GACGAAAGTG GTAGACCCTT TGGCTTTCGC CGATGTCTTC 
GTGGCTCTGG GTCCCCAGCA TCGAGCCTTC GGTCCCTACC GAGGGCGGGC CGAACTGCAG 
AATGACGGAC CTGGGGATGC CTCCCTGGTC CTCCGAAATG TCACCCTTCA GGACTACGGG 
CGCTACGAGT GCGAGGTCAC CAATGAGCTG GAGGATGACG TCGGCATGGT CAAGCTGGAT 
CTGGAAGGGG TGGTCTTCCC CTATCACCCG CGCGGAGGTC GCTACAAGAT GACTTTCGTG 
GAAGCGCAGC GTGCTTGTGC CGAACAGGAT GGCATTTTGG CGTCCGCGGA GCAGCTGCAC 
GCGGCCTGGC GCGATGGCCT GGACTGGTGC AACGCGGGAT GGTTACGCGA TGGCTCGGTG 
CAGTACCCAG TGAGCCATGC CCGGGAGCCC TGTGGCGGGA CTGGGAGCAC TGGAGCTGGT 
GGCGGCACCA ACGGGGGCGT GCGCAACTAT GGATATCGTC ATAACGCTGA GGAACGCTAC 
GATGCCTTCT GCTTCACGTC CAACCTCCCG GGCCGCGTGT TTTTCCTGAA ACCGCTGCGA 
CCTGTGGCCT TGGCCGGGGC AGTGCGCGCG TGCGCTGCGC GGGGTGCCAC AGTGGCCAAG 
GTCGGGCAGC TGTTCGCTGC GTGGAAGCTG CAGCTGTTGG ACCGCTGCAC TGCAGGCTGG 
CTGGCGGATG GCAGCGCGCG CTATCCCATC GTGAATCCGC GAACTCGCTG TGGAGGTCCT 
CGGCCCGGCG TGCGCAGCCT GGGTTTCCCT GACGCCTCCC GACGTCTCTT CGGTGTCTAC 
TGCTACCGCG CTCCAGGTGC CCCAGATCCG GCTCCAGGCG GCTGGGGCTG GGGCTGGGCC 
GGCGGAGGAG GTTGGGCTGG AGGGTCGAGG GATCCGGCTG CCTGGACCCC GCTGCGTGTA 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_808568.1
CDS	33..1235
Translation	MACAPGALGHRALWAVAWGLLLLVPVLAGAQRGRKKVVHVLEGESGSVVVQTAPGQVVSHRGGTIVLPCRYHYEAAAHGHDGVRLKWTKVVDPLAFADVFVALGPQHRAFGPYRGRAELQNDGPGDASLVLRNVTLQDYGRYECEVTNELEDDVGMVKLDLEGVVFPYHPRGGRYKMTFVEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVSHAREPCGGTGSTGAGGGTNGGVRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVALAGAVRACAARGATVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRTRCGGPRPGVRSLGFPDASRRLFGVYCYRAPGAPDPAPGGWGWGWAGGGGWAGGSRDPAAWTPLRV

Target ORF information:

RefSeq Version	NM_177900.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus hyaluronan and proteoglycan link protein 4 (Hapln4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_177900.4

ORF Insert Sequence:

ATGGCGTGTG CTCCAGGAGC CCTCGGTCAC CGCGCACTCT GGGCCGTGGC CTGGGGACTC 
CTGCTGCTGG TCCCCGTGCT CGCAGGGGCG CAGCGTGGCA GGAAGAAAGT CGTGCACGTG 
CTGGAGGGCG AGTCCGGTTC CGTGGTGGTG CAGACGGCGC CGGGGCAGGT GGTGAGCCAC 
CGCGGTGGTA CCATTGTCTT ACCCTGCCGT TACCACTACG AGGCGGCCGC CCACGGTCAC 
GACGGCGTCC GCCTCAAGTG GACGAAAGTG GTAGACCCTT TGGCTTTCGC CGATGTCTTC 
GTGGCTCTGG GTCCCCAGCA TCGAGCCTTC GGTCCCTACC GAGGGCGGGC CGAACTGCAG 
AATGACGGAC CTGGGGATGC CTCCCTGGTC CTCCGAAATG TCACCCTTCA GGACTACGGG 
CGCTACGAGT GCGAGGTCAC CAATGAGCTG GAGGATGACG TCGGCATGGT CAAGCTGGAT 
CTGGAAGGGG TGGTCTTCCC CTATCACCCG CGCGGAGGTC GCTACAAGAT GACTTTCGTG 
GAAGCGCAGC GTGCTTGTGC CGAACAGGAT GGCATTTTGG CGTCCGCGGA GCAGCTGCAC 
GCGGCCTGGC GCGATGGCCT GGACTGGTGC AACGCGGGAT GGTTACGCGA TGGCTCGGTG 
CAGTACCCAG TGAGCCATGC CCGGGAGCCC TGTGGCGGGA CTGGGAGCAC TGGAGCTGGT 
GGCGGCACCA ACGGGGGCGT GCGCAACTAT GGATATCGTC ATAACGCTGA GGAACGCTAC 
GATGCCTTCT GCTTCACGTC CAACCTCCCG GGCCGCGTGT TTTTCCTGAA ACCGCTGCGA 
CCTGTGGCCT TGGCCGGGGC AGTGCGCGCG TGCGCTGCGC GGGGTGCCAC AGTGGCCAAG 
GTCGGGCAGC TGTTCGCTGC GTGGAAGCTG CAGCTGTTGG ACCGCTGCAC TGCAGGCTGG 
CTGGCGGATG GCAGCGCGCG CTATCCCATC GTGAATCCGC GAACTCGCTG TGGAGGTCCT 
CGGCCCGGCG TGCGCAGCCT GGGTTTCCCT GACGCCTCCC GACGTCTCTT CGGTGTCTAC 
TGCTACCGCG CTCCAGGTGC CCCAGATCCG GCTCCAGGCG GCTGGGGCTG GGGCTGGGCC 
GGCGGAGGAG GTTGGGCTGG AGGGTCGAGG GATCCGGCTG CCTGGACCCC GCTGCGTGTA 
TAG