nr3c2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	nr3c2
Entrez Gene ID	562171
Full Name	nuclear receptor subfamily 3, group C, member 2
Synonyms	mr,si:ch211-189l17.1
General protein information	Preferred Names nuclear receptor subfamily 3, group C, member 2 Names mineralocorticoid receptor
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100403.1	NP_001093873.1	mineralocorticoid receptor

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	LOC100534796	XP_003197725.1
Canis lupus familiaris (dog)	NR3C2	XP_003639585.2
Gallus gallus (chicken)	NR3C2	NP_001152817.1
Macaca mulatta (Rhesus monkey)	NR3C2	XP_001099855.2
Pan troglodytes (chimpanzee)	NR3C2	XP_001150516.1
Mus musculus (house mouse)	Nr3c2	NP_001077375.1
Xenopus tropicalis (tropical clawed frog)	nr3c2	XP_002933547.2
Homo sapiens (human)	NR3C2	NP_000892.2
Bos taurus (cattle)	NR3C2	NP_001178278.1
Rattus norvegicus (Norway rat)	Nr3c2	NP_037263.1
Danio rerio (zebrafish)	nr3c2	NP_001093873.1

Gene Ontology
Bibliography

Related articles in PubMed

Glucocorticoid mixtures of fluticasone propionate, triamcinolone acetonide and clobetasol propionate induce additive effects in zebrafish embryos.
Willi RA, Salgueiro-González N, Carcaiso G, Fent K
Journal of hazardous materials374101-109(2019 Jul)

Environmental glucocorticoids corticosterone, betamethasone and flumethasone induce more potent physiological than transcriptional effects in zebrafish embryos.
Willi RA, Salgueiro-González N, Faltermann S, Hettich T, Fent K
The Science of the total environment672183-191(2019 Jul)

The mineralocorticoid receptor is essential for stress axis regulation in zebrafish larvae.
Faught E, Vijayan MM
Scientific reports8(1)18081(2018 12)

Transcriptional effects of androstenedione and 17α-hydroxyprogesterone in zebrafish embryos.
Fent K, Siegenthaler PF, Schmid AA
Aquatic toxicology (Amsterdam, Netherlands)2021-5(2018 Sep)

Evolution of human, chicken, alligator, frog, and zebrafish mineralocorticoid receptors: Allosteric influence on steroid specificity.
Katsu Y, Oka K, Baker ME
Science signaling11(537)(2018 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following nr3c2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nr3c2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01580	NM_001100403.1 Latest version!	Danio rerio nuclear receptor subfamily 3, group C, member 2 (nr3c2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

nr3c2 ( NM_001100403.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001093873.1 Danio rerio nuclear receptor subfamily 3, group C, member 2 (nr3c2), mRNA.

Price & Availability↑

CloneID	ODa01580
Clone ID Related Accession (Same CDS sequence)	NM_001100403.1
Accession Version	NM_001100403.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2913bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1576771200000
Organism	Danio rerio(zebrafish)
Product	mineralocorticoid receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF567113.1. On Aug 3, 2007 this sequence version replaced XM_685568.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF567113.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGAGACTA AAAGATACCA AAGTTGCTGC GAAGGGGCGA AAGCAGAAAA CAAATGGGCA 
CAGATGCCAA ACACCGCGGA CTATATCTGC TCTGCAGAAG AGAGTTTGAC AAACAGTGAT 
GTGCTCATGG ATATTGTTAA CTCGAGCAAT ACCCCTAATG TGCAATCTAT CTGCAAGGAC 
AACAACTTTA AGAATACAGA GGCAACAATG ATTAGAGTTA ACCAGAATCA ACCATTACCT 
TTCCCCACCT TCAACAACTG CTTCAACAAC CGCAAGTCAG AAACAGACTC AAAGGAACTT 
TCCAAAACAG TTGCAGAGTC AATGGGCTTG TACATGAATG CTGCCAGAGA GGCAGACTTT 
GGCTTTTCCC AACAAGGTGC TGCGGGAGGG CAGGGTAGCC CAGGGAAACT GTACCCTCTT 
TGTGGGAGAA CAAATGAAGA CAGCCAGGCC AAAACAAGTG GGAGCCCAAA GATGAAAGCT 
CCCCCTGCTT CATTCCCACC TGGGGCCCAA CTACCCAATG GTGGACCTCA GGAGTGTGCT 
GTGGTCTCTG ACTCAGTGCC CTCTGCTCTG GTCACTGCCC TTTCGTCCAG CACTGATGGG 
TCCTGTCCCA TGTCTAGTCC TACCGGACAC AACATGGTAT CATCCACCAC CAGCCCCACT 
TACTTTGACT CTGATTGTCC GACGCTAGAT TCTGCGACCA GCAGCTTGAC CCATTGTCAA 
CACACCAGCC CCAACATTTG CAGCCCAGTA AAGTCCAGCA TTGTGGGGTC ACCTCCACTG 
CCTAGTCCCC TCAGTGTAAT GAAGTCTCCG GTTTCCAGTC CTCATAGTAT AGGCAGCGTG 
AGGTCACCGC TTTCCTGTAA CACCAACATG AGGTCATCTG TCTCAAGCCC AACAACAAAT 
GGAGGCAATA CCTGTAATAT TAAACCATCC ATTTCCAGCC CGCCCACTGC TGGCAGCATG 
TCCATGTCCA GTCCCAGGAA CTCATCCAGG GGTTTCTCAG TCTCCAGCCC ACCCAGTGGA 
TTGGGCCTAG TGCAAAATGA TGTCAACAGC CCTGAGAGCC GAGAGCACGA CTTCAAGGGA 
TTCGAGTTCC CGAAGGTAGA GAATGTGGAT GGGGAGATCT TTAACATCGG CTTGGATGCT 
ATGGGAGTGG CTAAATATAT CAAAAATGAA CCTGGCACTG ATTTCAGGAG TATGTGCCTA 
GGCAGCAGCA AGAGTGCCAT GTCAAATTCA CCTTTCGTAA CTCACATTAA GACCGAGCCA 
AACAGAGAGG TGACTTGCTC GAACCTCCAG TTTGCTGAAC CGCAGCACTC TCTGGGCTGC 
TTTCCTTCGA CAGAGACCAC ATACTTGTCT TTGAGGGATA ATATTGACGA ATATAGTCTT 
TCTGGGATCT TGGGACCTCC TGTTTCGTCT CTGAATGGCA ACTATGAACC TGGTGTGTTT 
CCTAACAATG GCCTGCCCAA GGGGATTAAA CAGGAAACCA ATGATGGCAG CTATTACCAA 
GAGAATAATA ATGTGCCCAC TTCGGCTATT GTTGGCGTTA ATTCAGGTGG ACATTCATTT 
CATTACCAGA TTGGAGCGCA AGGAACAATG TCGTTTTCAC GCCACAATTT GAGGGACCAG 
ACAAACCCCT TGTTGAATCT AATTTCTCCA GTTACTGGAT TAATGGAGAC GTGGAAAACT 
CGCCCAGGCC TGTCACAGGG GCCCCTCACT GCTAGAGGGG ACGGGTATCC AGGCGCAGTC 
TGCCTTACAG AAAACATGGA AAGTGCGTCG CTGAGGCACA CGTCTTCGAC AGCCAAAGTG 
TGTCTGGTGT GTGGAGACGA GGCGTCAGGA TGCCACTACG GGGTTGTTAC ATGTGGAAGT 
TGCAAAGTTT TCTTCAAAAG AGCGGTAGAA GGTCAGCACA ACTACCTTTG TGCTGGGAGG 
AATGACTGCA TCATTGACAA GATTCGGCGG AAAAACTGTC CGGCCTGCAG AGTACGCAAG 
TGTCTACAAG CTGGGATGAA TCTTGGGGCA CGGAAGTCGA AGAAGTTGGG GAAAATAAAG 
AGCATTAGTG AAGATTCTTC CCTGCAGAGC TCAAAGGATG GCCCGTTTTT GACATCCGAA 
AAGGAGTTGA GTTCCTCCAC CGCTCTCGTA CCACACACCC CGACGGTCGC CCCATATCTG 
ACGCCGTCCG TCTGCAGCGT TCTGGAGCTC ATAGAGCCAG AAGTGGTGTT CGCTGGCTAT 
GATAACACAC AACCTGACAC AACAGACCAC CTGCTTACCA GCCTCAACCA GCTCGCCGGA 
AAACAGATGA TCCGAGTGGT CAAGTGGGCC AAAGTACTTC CAGGTTTCCG CAGTCTACCC 
ATTGAGGACC AAATCACGCT GATCCAGTAT TCCTGGATGT GTCTCTCCTC CTTCTCCCTC 
AGCTGGAGAT CCTACAAACA CACCAACGCC CAAATGCTCT ACTTCGCCCC GGATCTAGTC 
TTCAACGAGG AGCGAATGCA GCAGTCTGCC ATGTATGATC TGTGTGTGGG GATGCGGCAG 
GTGAGCCAGG AGTTTGTTCG TCTTCAGCTC ACATATGAGG AATATCTGGC CATGAAGGTT 
CTGCTGCTGC TCAGCACAGT GCCCAAAGAT GGTCTGAAGA ACCAAGGGGC ATTTGAGGAG 
ATGCGGGTGA ATTATATTAA GGAGCTCCGC CGCTCTGTTG GGAAAGCCAC TAACAATTCT 
GGCCAAACAT GGCAGCGCTT CTTCCAGCTG ACAAAACTTC TGGACGCCAC GCATGATCTT 
GTTCGGAGCC TGTTGGACTT TTGTTTCTAC ACTTTCCGCG AATCCCAGGC TCTGAAGGTT 
GAGTTTCCCG AGATGCTGGT GGAAATTATC AGCGACCAGA TACCAAAGGT GGAGTCGGGT 
CAAACACACA CTCTCTACTT TCATAAGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093873.1
CDS	334..3246
Translation	METKRYQSCCEGAKAENKWAQMPNTADYICSAEESLTNSDVLMDIVNSSNTPNVQSICKDNNFKNTEATMIRVNQNQPLPFPTFNNCFNNRKSETDSKELSKTVAESMGLYMNAAREADFGFSQQGAAGGQGSPGKLYPLCGRTNEDSQAKTSGSPKMKAPPASFPPGAQLPNGGPQECAVVSDSVPSALVTALSSSTDGSCPMSSPTGHNMVSSTTSPTYFDSDCPTLDSATSSLTHCQHTSPNICSPVKSSIVGSPPLPSPLSVMKSPVSSPHSIGSVRSPLSCNTNMRSSVSSPTTNGGNTCNIKPSISSPPTAGSMSMSSPRNSSRGFSVSSPPSGLGLVQNDVNSPESREHDFKGFEFPKVENVDGEIFNIGLDAMGVAKYIKNEPGTDFRSMCLGSSKSAMSNSPFVTHIKTEPNREVTCSNLQFAEPQHSLGCFPSTETTYLSLRDNIDEYSLSGILGPPVSSLNGNYEPGVFPNNGLPKGIKQETNDGSYYQENNNVPTSAIVGVNSGGHSFHYQIGAQGTMSFSRHNLRDQTNPLLNLISPVTGLMETWKTRPGLSQGPLTARGDGYPGAVCLTENMESASLRHTSSTAKVCLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRVRKCLQAGMNLGARKSKKLGKIKSISEDSSLQSSKDGPFLTSEKELSSSTALVPHTPTVAPYLTPSVCSVLELIEPEVVFAGYDNTQPDTTDHLLTSLNQLAGKQMIRVVKWAKVLPGFRSLPIEDQITLIQYSWMCLSSFSLSWRSYKHTNAQMLYFAPDLVFNEERMQQSAMYDLCVGMRQVSQEFVRLQLTYEEYLAMKVLLLLSTVPKDGLKNQGAFEEMRVNYIKELRRSVGKATNNSGQTWQRFFQLTKLLDATHDLVRSLLDFCFYTFRESQALKVEFPEMLVEIISDQIPKVESGQTHTLYFHKK

Target ORF information:

RefSeq Version	NM_001100403.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio nuclear receptor subfamily 3, group C, member 2 (nr3c2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100403.1

ORF Insert Sequence:

ATGGAGACTA AAAGATACCA AAGTTGCTGC GAAGGGGCGA AAGCAGAAAA CAAATGGGCA 
CAGATGCCAA ACACCGCGGA CTATATCTGC TCTGCAGAAG AGAGTTTGAC AAACAGTGAT 
GTGCTCATGG ATATTGTTAA CTCGAGCAAT ACCCCTAATG TGCAATCTAT CTGCAAGGAC 
AACAACTTTA AGAATACAGA GGCAACAATG ATTAGAGTTA ACCAGAATCA ACCATTACCT 
TTCCCCACCT TCAACAACTG CTTCAACAAC CGCAAGTCAG AAACAGACTC AAAGGAACTT 
TCCAAAACAG TTGCAGAGTC AATGGGCTTG TACATGAATG CTGCCAGAGA GGCAGACTTT 
GGCTTTTCCC AACAAGGTGC TGCGGGAGGG CAGGGTAGCC CAGGGAAACT GTACCCTCTT 
TGTGGGAGAA CAAATGAAGA CAGCCAGGCC AAAACAAGTG GGAGCCCAAA GATGAAAGCT 
CCCCCTGCTT CATTCCCACC TGGGGCCCAA CTACCCAATG GTGGACCTCA GGAGTGTGCT 
GTGGTCTCTG ACTCAGTGCC CTCTGCTCTG GTCACTGCCC TTTCGTCCAG CACTGATGGG 
TCCTGTCCCA TGTCTAGTCC TACCGGACAC AACATGGTAT CATCCACCAC CAGCCCCACT 
TACTTTGACT CTGATTGTCC GACGCTAGAT TCTGCGACCA GCAGCTTGAC CCATTGTCAA 
CACACCAGCC CCAACATTTG CAGCCCAGTA AAGTCCAGCA TTGTGGGGTC ACCTCCACTG 
CCTAGTCCCC TCAGTGTAAT GAAGTCTCCG GTTTCCAGTC CTCATAGTAT AGGCAGCGTG 
AGGTCACCGC TTTCCTGTAA CACCAACATG AGGTCATCTG TCTCAAGCCC AACAACAAAT 
GGAGGCAATA CCTGTAATAT TAAACCATCC ATTTCCAGCC CGCCCACTGC TGGCAGCATG 
TCCATGTCCA GTCCCAGGAA CTCATCCAGG GGTTTCTCAG TCTCCAGCCC ACCCAGTGGA 
TTGGGCCTAG TGCAAAATGA TGTCAACAGC CCTGAGAGCC GAGAGCACGA CTTCAAGGGA 
TTCGAGTTCC CGAAGGTAGA GAATGTGGAT GGGGAGATCT TTAACATCGG CTTGGATGCT 
ATGGGAGTGG CTAAATATAT CAAAAATGAA CCTGGCACTG ATTTCAGGAG TATGTGCCTA 
GGCAGCAGCA AGAGTGCCAT GTCAAATTCA CCTTTCGTAA CTCACATTAA GACCGAGCCA 
AACAGAGAGG TGACTTGCTC GAACCTCCAG TTTGCTGAAC CGCAGCACTC TCTGGGCTGC 
TTTCCTTCGA CAGAGACCAC ATACTTGTCT TTGAGGGATA ATATTGACGA ATATAGTCTT 
TCTGGGATCT TGGGACCTCC TGTTTCGTCT CTGAATGGCA ACTATGAACC TGGTGTGTTT 
CCTAACAATG GCCTGCCCAA GGGGATTAAA CAGGAAACCA ATGATGGCAG CTATTACCAA 
GAGAATAATA ATGTGCCCAC TTCGGCTATT GTTGGCGTTA ATTCAGGTGG ACATTCATTT 
CATTACCAGA TTGGAGCGCA AGGAACAATG TCGTTTTCAC GCCACAATTT GAGGGACCAG 
ACAAACCCCT TGTTGAATCT AATTTCTCCA GTTACTGGAT TAATGGAGAC GTGGAAAACT 
CGCCCAGGCC TGTCACAGGG GCCCCTCACT GCTAGAGGGG ACGGGTATCC AGGCGCAGTC 
TGCCTTACAG AAAACATGGA AAGTGCGTCG CTGAGGCACA CGTCTTCGAC AGCCAAAGTG 
TGTCTGGTGT GTGGAGACGA GGCGTCAGGA TGCCACTACG GGGTTGTTAC ATGTGGAAGT 
TGCAAAGTTT TCTTCAAAAG AGCGGTAGAA GGTCAGCACA ACTACCTTTG TGCTGGGAGG 
AATGACTGCA TCATTGACAA GATTCGGCGG AAAAACTGTC CGGCCTGCAG AGTACGCAAG 
TGTCTACAAG CTGGGATGAA TCTTGGGGCA CGGAAGTCGA AGAAGTTGGG GAAAATAAAG 
AGCATTAGTG AAGATTCTTC CCTGCAGAGC TCAAAGGATG GCCCGTTTTT GACATCCGAA 
AAGGAGTTGA GTTCCTCCAC CGCTCTCGTA CCACACACCC CGACGGTCGC CCCATATCTG 
ACGCCGTCCG TCTGCAGCGT TCTGGAGCTC ATAGAGCCAG AAGTGGTGTT CGCTGGCTAT 
GATAACACAC AACCTGACAC AACAGACCAC CTGCTTACCA GCCTCAACCA GCTCGCCGGA 
AAACAGATGA TCCGAGTGGT CAAGTGGGCC AAAGTACTTC CAGGTTTCCG CAGTCTACCC 
ATTGAGGACC AAATCACGCT GATCCAGTAT TCCTGGATGT GTCTCTCCTC CTTCTCCCTC 
AGCTGGAGAT CCTACAAACA CACCAACGCC CAAATGCTCT ACTTCGCCCC GGATCTAGTC 
TTCAACGAGG AGCGAATGCA GCAGTCTGCC ATGTATGATC TGTGTGTGGG GATGCGGCAG 
GTGAGCCAGG AGTTTGTTCG TCTTCAGCTC ACATATGAGG AATATCTGGC CATGAAGGTT 
CTGCTGCTGC TCAGCACAGT GCCCAAAGAT GGTCTGAAGA ACCAAGGGGC ATTTGAGGAG 
ATGCGGGTGA ATTATATTAA GGAGCTCCGC CGCTCTGTTG GGAAAGCCAC TAACAATTCT 
GGCCAAACAT GGCAGCGCTT CTTCCAGCTG ACAAAACTTC TGGACGCCAC GCATGATCTT 
GTTCGGAGCC TGTTGGACTT TTGTTTCTAC ACTTTCCGCG AATCCCAGGC TCTGAAGGTT 
GAGTTTCCCG AGATGCTGGT GGAAATTATC AGCGACCAGA TACCAAAGGT GGAGTCGGGT 
CAAACACACA CTCTCTACTT TCATAAGAAA TGA