ERBB2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERBB2
Entrez Gene ID	403883
Full Name	erb-b2 receptor tyrosine kinase 2
Synonyms	HER-2,c-erbB-2,p185erbB2
General protein information	Preferred Names erb-b2 receptor tyrosine kinase 2 Names receptor tyrosine-protein kinase erbB-2 proto-oncogene c-ErbB-2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003217.2	NP_001003217.2	receptor tyrosine-protein kinase erbB-2 precursor
XM_022422534.1	XP_022278242.1	receptor tyrosine-protein kinase erbB-2 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ERBB2	XP_003315512.2
Mus musculus (house mouse)	Erbb2	NP_001003817.1
Macaca mulatta (Rhesus monkey)	ERBB2	XP_001090430.1
Rattus norvegicus (Norway rat)	Erbb2	NP_058699.2
Danio rerio (zebrafish)	erbb2	NP_956413.2
Homo sapiens (human)	ERBB2	NP_004439.2
Canis lupus familiaris (dog)	ERBB2	NP_001003217.1
Gallus gallus (chicken)	ERBB2	NP_001038126.1
Bos taurus (cattle)	ERBB2	XP_003587474.1
Xenopus tropicalis (tropical clawed frog)	erbb2	XP_002940420.2

Gene Ontology
Bibliography

Related articles in PubMed

HER-2 and EGFR mRNA Expression and Its Relationship with Versican in Malignant Matrix-Producing Tumors of the Canine Mammary Gland.
Damasceno KA, Ferreira E, Estrela-Lima A, Gamba Cde O, Miranda FF, Alves MR, Rocha RM, de Barros AL, Cassali GD
PloS one11(8)e0160419(2016)

Investigation of HER2 expression in canine mammary tumors by antibody-based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer?
Burrai GP, Tanca A, De Miglio MR, Abbondio M, Pisanu S, Polinas M, Pirino S, Mohammed SI, Uzzau S, Addis MF, Antuofermo E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine36(11)9083-91(2015 Nov)

Molecular phenotype of primary mammary tumours and distant metastases in female dogs and cats.
Beha G, Muscatello LV, Brunetti B, Asproni P, Millanta F, Poli A, Benazzi C, Sarli G
Journal of comparative pathology150(2-3)194-7(2014 Feb-Apr)

HER-2 expression in canine morphologically normal, hyperplastic and neoplastic mammary tissues and its correlation with the clinical outcome.
Ressel L, Puleio R, Loria GR, Vannozzi I, Millanta F, Caracappa S, Poli A
Research in veterinary science94(2)299-305(2013 Apr)

Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.
Gordon LI, Burke MA, Singh AT, Prachand S, Lieberman ED, Sun L, Naik TJ, Prasad SV, Ardehali H
The Journal of biological chemistry284(4)2080-7(2009 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ERBB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERBB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe191403	NM_001003217.2 Latest version!	Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OCe290373	XM_022422534.1 Latest version!	Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERBB2 ( NM_001003217.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003217.2 Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.

Price & Availability↑

CloneID	OCe191403
Clone ID Related Accession (Same CDS sequence)	NM_001003217.2
Accession Version	NM_001003217.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1550937600000
Organism	Canis lupus familiaris(dog)
Product	receptor tyrosine-protein kinase erbB-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03006470.1. On Sep 1, 2015 this sequence version replaced NM_001003217.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AB008451.1, EU239091.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTTCTCG CCCTCCTGCC CTCCGGAGCC 
GCGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTCC GGCTCCCGGC CAGTCCCGAG 
ACCCACCTGG ATATGCTCCG CCACCTGTAC CAGGGCTGTC AAGTGGTACA GGGGAACCTG 
GAGCTCACTT ACCTGCCTGC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAGGGCTATG TGCTCATTGC TCACAGCCAA GTGAGGCAGA TCCCACTGCA GAGGCTACGA 
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGG AGGGTGGCAT CCCTGCACCA GGGGCGGCCC CAGGAGGGCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCCTGAAG GGAGGGGTCT TGATTCAGCG GAGCCCGCAG 
CTCTGCCACC AGGACACGAT TTTATGGAAG GACGTCTTCC ATAAGAACAA CCAGCTGGCC 
CTCACGCTGA TAGACACCAA CCGCTCTCGG GCCTGCCCAC CCTGTTCTCC AGCTTGTAAA 
GACGCCCACT GCTGGGGGGC CAGCTCCGGG GACTGTCAGA GCTTGACGCG GACTGTCTGT 
GCGGGGGGCT GTGCCCGCTG CAAGGGCCCA CAACCCACCG ACTGCTGCCA CGAGCAGTGT 
GCTGCTGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTTCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACGGA CACCTTCGAA 
TCCATGCCCA ACCCTGAGGG CCGATATACC TTCGGGGCCA GCTGTGTGAC CTCCTGTCCC 
TACAACTACC TGTCTACGGA TGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACGG CTGAGGATGG GACACAGCGG TGCGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GTCTGGGCAT GGAGCACCTG CGGGAGGTGA GAGCGGTCAC CAGTGCGAAC 
ATCCAGGAGT TTGCCGGCTG CAAGAAGATC TTTGGAAGCC TGGCATTTTT GCCAGAGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTACAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATCAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCCTGCCT 
AACCTCAGTG TCTTCCAGAA CCTGCGAGTA ATCCGGGGAC GAGTTCTGCA TGATGGTGCC 
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAA 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACGCCCGCC TTTGCTTCGT GCACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCATAGTGC CAACCGGCCA 
GAGGAGGAGT GCGTGGGCGA GGGCCTGGCC TGCTACCCGC TGTGCGCCCA TGGGCACTGC 
TGGGGTCCAG GGCCGACCCA GTGCGTCAAC TGCAGCCAAT TCCTTCGGGG CCAGGAGTGC 
GTGGAAGAAT GCCGAGTACT GCAGGGGCTG CCCCGAGAGT ATGTGAAGGA CAGGTACTGT 
CTGCCGTGCC ACTCAGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT CGGATCGGAG 
GCTGACCAGT GTGTGGCCTG CGCCCACTAC AAGGACCCTC CCTTCTGTGT GGCTCGCTGC 
CCCAGTGGTG TGAAACCTGA CCTGTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACTTGCC AGCCGTGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGTCCCG CCGAGCAGAG AGCCAGCCCT GTGACATCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG CTGTGGTCGT GGGGCTGGTC CTCGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACTAT GCGGAGGCTG CTGCAGGAAA CCGAGCTGGT GGAGCCGCTG 
ACGCCTAGTG GAGCGATGCC CAACCAGGCT CAGATGCGGA TCCTGAAAGA GACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACAG TCTACAAGGG CATCTGGATC 
CCTGATGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCATATGTGA TGGCTGGAGT GGGCTCCCCG 
TATGTGTCCC GCCTCCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT 
ATGCCCTACG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT GGGCTCCCAG 
GACTTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTCCGG 
CTGGTGCACA GGGACCTGGC TGCCCGGAAT GTGCTGGTCA AGAGTCCCAA CCATGTCAAG 
ATTACAGATT TCGGGCTGGC TCGGTTGCTG GACATCGACG AGACAGAGTA CCATGCGGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCC TTCTCCGCCG GCGGTTCACC 
CACCAGAGTG ATGTGTGGAG CTATGGTGTG ACTGTGTGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA GTGCTGGATG 
ATAGACTCTG AATGCCGACC CCGGTTCCGG GAGTTGGTGG CCGAATTCTC ACGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATTCAG AATGAAGACT TGGGCCCCGC CAGCCCCTTG 
GACAGCACCT TCTACCGTTC ACTACTGGAA GATGATGACA TGGGGGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG AACCTACCCC AGGGGCTGGG 
GGCACTGCCC ACCGACGGCA CCGCAGCTCA TCCACCAGGA GTGGCGGTGG TGAGCTGACT 
CTAGGACTGG AGCCCTCCGA GGAGGAGCCC CCCAAGTCTC CACTGGCACC CTCAGAGGGC 
GCTGGCTCTG ACGTGTTTGA TGGTGACTTG GGAATGGGGG CAGCCAAGGG GCTGCAGAGC 
CTTCCCTCAC AGGACCCCAG CCCTCTCCAG CGGTACAGTG AGGACCCTAC GGTACCCTTG 
CCCCCTGAGA CTGATGGCTA CGTCGCCCCC CTGACCTGCA GCCCCCAGCC TGAATATGTG 
AACCAGCCAG AAGTTTGGCC GCAGCCCCCC TCGCCCCTAG AAGGCCCTCT GCCTCCTTCC 
CGACCGGCTG GTGCCACTCT GGAAAGGCCC AAGACTCTGT CCCCCAAGAC TCTCTCCCCT 
GGCAAGAATG GGGTTGTCAA AGACGTTTTT GCCTTTGGGA GTGCTGTGGA GAATCCGGAG 
TACCTGGCAC CCCGGGGCAG AGCTGCCCCT CAGCCCCACC CTCCTCCAGC CTTCAGCCCA 
GCCTTTGACA ACCTGTATTA CTGGGACCAG GATCCATCAG AGCGGGGCTC TCCACCCAGC 
ACCTTTGAAG GGACCCCTAC AGCAGAGAAC CCGGAGTACC TGGGGCTGGA CGTGCCAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003217.2
CDS	157..3939
Translation	MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQIPLQRLRIVRGTQLFEDNYALAVLDNGDPLEGGIPAPGAAPGGLRELQLRSLTEILKGGVLIQRSPQLCHQDTILWKDVFHKNNQLALTLIDTNRSRACPPCSPACKDAHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTSCPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFVHTVPWDQLFRNPHQALLHSANRPEEECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVKDRYCLPCHSECQPQNGSVTCFGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESLLRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPEPTPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPSQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPEYLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV

Target ORF information:

RefSeq Version	NM_001003217.2
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003217.2

ORF Insert Sequence:

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTTCTCG CCCTCCTGCC CTCCGGAGCC 
GCGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTCC GGCTCCCGGC CAGTCCCGAG 
ACCCACCTGG ATATGCTCCG CCACCTGTAC CAGGGCTGTC AAGTGGTACA GGGGAACCTG 
GAGCTCACTT ACCTGCCTGC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAGGGCTATG TGCTCATTGC TCACAGCCAA GTGAGGCAGA TCCCACTGCA GAGGCTACGA 
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGG AGGGTGGCAT CCCTGCACCA GGGGCGGCCC CAGGAGGGCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCCTGAAG GGAGGGGTCT TGATTCAGCG GAGCCCGCAG 
CTCTGCCACC AGGACACGAT TTTATGGAAG GACGTCTTCC ATAAGAACAA CCAGCTGGCC 
CTCACGCTGA TAGACACCAA CCGCTCTCGG GCCTGCCCAC CCTGTTCTCC AGCTTGTAAA 
GACGCCCACT GCTGGGGGGC CAGCTCCGGG GACTGTCAGA GCTTGACGCG GACTGTCTGT 
GCGGGGGGCT GTGCCCGCTG CAAGGGCCCA CAACCCACCG ACTGCTGCCA CGAGCAGTGT 
GCTGCTGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTTCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACGGA CACCTTCGAA 
TCCATGCCCA ACCCTGAGGG CCGATATACC TTCGGGGCCA GCTGTGTGAC CTCCTGTCCC 
TACAACTACC TGTCTACGGA TGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACGG CTGAGGATGG GACACAGCGG TGCGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GTCTGGGCAT GGAGCACCTG CGGGAGGTGA GAGCGGTCAC CAGTGCGAAC 
ATCCAGGAGT TTGCCGGCTG CAAGAAGATC TTTGGAAGCC TGGCATTTTT GCCAGAGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTACAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATCAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCCTGCCT 
AACCTCAGTG TCTTCCAGAA CCTGCGAGTA ATCCGGGGAC GAGTTCTGCA TGATGGTGCC 
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAA 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACGCCCGCC TTTGCTTCGT GCACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCATAGTGC CAACCGGCCA 
GAGGAGGAGT GCGTGGGCGA GGGCCTGGCC TGCTACCCGC TGTGCGCCCA TGGGCACTGC 
TGGGGTCCAG GGCCGACCCA GTGCGTCAAC TGCAGCCAAT TCCTTCGGGG CCAGGAGTGC 
GTGGAAGAAT GCCGAGTACT GCAGGGGCTG CCCCGAGAGT ATGTGAAGGA CAGGTACTGT 
CTGCCGTGCC ACTCAGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT CGGATCGGAG 
GCTGACCAGT GTGTGGCCTG CGCCCACTAC AAGGACCCTC CCTTCTGTGT GGCTCGCTGC 
CCCAGTGGTG TGAAACCTGA CCTGTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACTTGCC AGCCGTGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGTCCCG CCGAGCAGAG AGCCAGCCCT GTGACATCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG CTGTGGTCGT GGGGCTGGTC CTCGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACTAT GCGGAGGCTG CTGCAGGAAA CCGAGCTGGT GGAGCCGCTG 
ACGCCTAGTG GAGCGATGCC CAACCAGGCT CAGATGCGGA TCCTGAAAGA GACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACAG TCTACAAGGG CATCTGGATC 
CCTGATGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCATATGTGA TGGCTGGAGT GGGCTCCCCG 
TATGTGTCCC GCCTCCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT 
ATGCCCTACG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT GGGCTCCCAG 
GACTTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTCCGG 
CTGGTGCACA GGGACCTGGC TGCCCGGAAT GTGCTGGTCA AGAGTCCCAA CCATGTCAAG 
ATTACAGATT TCGGGCTGGC TCGGTTGCTG GACATCGACG AGACAGAGTA CCATGCGGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCC TTCTCCGCCG GCGGTTCACC 
CACCAGAGTG ATGTGTGGAG CTATGGTGTG ACTGTGTGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA GTGCTGGATG 
ATAGACTCTG AATGCCGACC CCGGTTCCGG GAGTTGGTGG CCGAATTCTC ACGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATTCAG AATGAAGACT TGGGCCCCGC CAGCCCCTTG 
GACAGCACCT TCTACCGTTC ACTACTGGAA GATGATGACA TGGGGGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG AACCTACCCC AGGGGCTGGG 
GGCACTGCCC ACCGACGGCA CCGCAGCTCA TCCACCAGGA GTGGCGGTGG TGAGCTGACT 
CTAGGACTGG AGCCCTCCGA GGAGGAGCCC CCCAAGTCTC CACTGGCACC CTCAGAGGGC 
GCTGGCTCTG ACGTGTTTGA TGGTGACTTG GGAATGGGGG CAGCCAAGGG GCTGCAGAGC 
CTTCCCTCAC AGGACCCCAG CCCTCTCCAG CGGTACAGTG AGGACCCTAC GGTACCCTTG 
CCCCCTGAGA CTGATGGCTA CGTCGCCCCC CTGACCTGCA GCCCCCAGCC TGAATATGTG 
AACCAGCCAG AAGTTTGGCC GCAGCCCCCC TCGCCCCTAG AAGGCCCTCT GCCTCCTTCC 
CGACCGGCTG GTGCCACTCT GGAAAGGCCC AAGACTCTGT CCCCCAAGAC TCTCTCCCCT 
GGCAAGAATG GGGTTGTCAA AGACGTTTTT GCCTTTGGGA GTGCTGTGGA GAATCCGGAG 
TACCTGGCAC CCCGGGGCAG AGCTGCCCCT CAGCCCCACC CTCCTCCAGC CTTCAGCCCA 
GCCTTTGACA ACCTGTATTA CTGGGACCAG GATCCATCAG AGCGGGGCTC TCCACCCAGC 
ACCTTTGAAG GGACCCCTAC AGCAGAGAAC CCGGAGTACC TGGGGCTGGA CGTGCCAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERBB2 ( XM_022422534.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022278242.1 Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe290373
Clone ID Related Accession (Same CDS sequence)	XM_022422534.1
Accession Version	XM_022422534.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1504454400000
Organism	Canis lupus familiaris(dog)
Product	receptor tyrosine-protein kinase erbB-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006591.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTTCTCG CCCTCCTGCC CTCCGGAGCC 
GCGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTCC GGCTCCCGGC CAGTCCCGAG 
ACCCACCTGG ATATGCTCCG CCACCTGTAC CAGGGCTGTC AAGTGGTACA GGGGAACCTG 
GAGCTCACTT ACCTGCCTGC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAGGGCTATG TGCTCATTGC TCACAGCCAA GTGAGGCAGA TCCCACTGCA GAGGCTACGA 
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGG AGGGTGGCAT CCCTGCACCA GGGGCGGCCC CAGGAGGGCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCCTGAAG GGAGGGGTCT TGATTCAGCG GAGCCCGCAG 
CTCTGCCACC AGGACACGAT TTTATGGAAG GACGTCTTCC ATAAGAACAA CCAGCTGGCC 
CTCACGCTGA TAGACACCAA CCGCTCTCGG GCCTGCCCAC CCTGTTCTCC AGCTTGTAAA 
GACGCCCACT GCTGGGGGGC CAGCTCCGGG GACTGTCAGA GCTTGACGCG GACTGTCTGT 
GCGGGGGGCT GTGCCCGCTG CAAGGGCCCA CAACCCACCG ACTGCTGCCA CGAGCAGTGT 
GCTGCTGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTTCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACGGA CACCTTCGAA 
TCCATGCCCA ACCCTGAGGG CCGATATACC TTCGGGGCCA GCTGTGTGAC CTCCTGTCCC 
TACAACTACC TGTCTACGGA TGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACGG CTGAGGATGG GACACAGCGG TGCGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GTCTGGGCAT GGAGCACCTG CGGGAGGTGA GAGCGGTCAC CAGTGCGAAC 
ATCCAGGAGT TTGCCGGCTG CAAGAAGATC TTTGGAAGCC TGGCATTTTT GCCAGAGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTACAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATCAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCCTGCCT 
AACCTCAGTG TCTTCCAGAA CCTGCGAGTA ATCCGGGGAC GAGTTCTGCA TGATGGTGCC 
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAA 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACGCCCGCC TTTGCTTCGT GCACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCATAGTGC CAACCGGCCA 
GAGGAGGAGT GCGTGGGCGA GGGCCTGGCC TGCTACCCGC TGTGCGCCCA TGGGCACTGC 
TGGGGTCCAG GGCCGACCCA GTGCGTCAAC TGCAGCCAAT TCCTTCGGGG CCAGGAGTGC 
GTGGAAGAAT GCCGAGTACT GCAGGGGCTG CCCCGAGAGT ATGTGAAGGA CAGGTACTGT 
CTGCCGTGCC ACTCAGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT CGGATCGGAG 
GCTGACCAGT GTGTGGCCTG CGCCCACTAC AAGGACCCTC CCTTCTGTGT GGCTCGCTGC 
CCCAGTGGTG TGAAACCTGA CCTGTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACTTGCC AGCCGTGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGTCCCG CCGAGCAGAG AGCCAGCCCT GTGACATCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG CTGTGGTCGT GGGGCTGGTC CTCGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACTAT GCGGAGGCTG CTGCAGGAAA CCGAGCTGGT GGAGCCGCTG 
ACGCCTAGTG GAGCGATGCC CAACCAGGCT CAGATGCGGA TCCTGAAAGA GACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACAG TCTACAAGGG CATCTGGATC 
CCTGATGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCATATGTGA TGGCTGGAGT GGGCTCCCCG 
TATGTGTCCC GCCTCCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT 
ATGCCCTACG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT GGGCTCCCAG 
GACTTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTCCGG 
CTGGTGCACA GGGACCTGGC TGCCCGGAAT GTGCTGGTCA AGAGTCCCAA CCATGTCAAG 
ATTACAGATT TCGGGCTGGC TCGGTTGCTG GACATCGACG AGACAGAGTA CCATGCGGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCC TTCTCCGCCG GCGGTTCACC 
CACCAGAGTG ATGTGTGGAG CTATGGTGTG ACTGTGTGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA GTGCTGGATG 
ATAGACTCTG AATGCCGACC CCGGTTCCGG GAGTTGGTGG CCGAATTCTC ACGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATTCAG AATGAAGACT TGGGCCCCGC CAGCCCCTTG 
GACAGCACCT TCTACCGTTC ACTACTGGAA GATGATGACA TGGGGGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG AACCTACCCC AGGGGCTGGG 
GGCACTGCCC ACCGACGGCA CCGCAGCTCA TCCACCAGGG TCAGTGTCCT CTGTCACACT 
GAGAGTGGCG GTGGTGAGCT GACTCTAGGA CTGGAGCCCT CCGAGGAGGA GCCCCCCAAG 
TCTCCACTGG CACCCTCAGA GGGCGCTGGC TCTGACGTGT TTGATGGTGA CTTGGGAATG 
GGGGCAGCCA AGGGGCTGCA GAGCCTTCCC TCACAGGACC CCAGCCCTCT CCAGCGGTAC 
AGTGAGGACC CTACGGTACC CTTGCCCCCT GAGACTGATG GCTACGTCGC CCCCCTGACC 
TGCAGCCCCC AGCCTGAATA TGTGAACCAG CCAGAAGTTT GGCCGCAGCC CCCCTCGCCC 
CTAGAAGGCC CTCTGCCTCC TTCCCGACCG GCTGGTGCCA CTCTGGAAAG GCCCAAGACT 
CTGTCCCCCA AGACTCTCTC CCCTGGCAAG AATGGGGTTG TCAAAGACGT TTTTGCCTTT 
GGGAGTGCTG TGGAGAATCC GGAGTACCTG GCACCCCGGG GCAGAGCTGC CCCTCAGCCC 
CACCCTCCTC CAGCCTTCAG CCCAGCCTTT GACAACCTGT ATTACTGGGA CCAGGATCCA 
TCAGAGCGGG GCTCTCCACC CAGCACCTTT GAAGGGACCC CTACAGCAGA GAACCCGGAG 
TACCTGGGGC TGGACGTGCC AGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022278242.1
CDS	230..4036
Translation	MELAAWCRWGLLLALLPSGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQIPLQRLRIVRGTQLFEDNYALAVLDNGDPLEGGIPAPGAAPGGLRELQLRSLTEILKGGVLIQRSPQLCHQDTILWKDVFHKNNQLALTLIDTNRSRACPPCSPACKDAHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTSCPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFVHTVPWDQLFRNPHQALLHSANRPEEECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVKDRYCLPCHSECQPQNGSVTCFGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESLLRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPEPTPGAGGTAHRRHRSSSTRVSVLCHTESGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPSQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPEYLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV

Target ORF information:

RefSeq Version	XM_022422534.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022422534.1

ORF Insert Sequence:

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTTCTCG CCCTCCTGCC CTCCGGAGCC 
GCGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTCC GGCTCCCGGC CAGTCCCGAG 
ACCCACCTGG ATATGCTCCG CCACCTGTAC CAGGGCTGTC AAGTGGTACA GGGGAACCTG 
GAGCTCACTT ACCTGCCTGC CAATGCCAGC CTGTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAGGGCTATG TGCTCATTGC TCACAGCCAA GTGAGGCAGA TCCCACTGCA GAGGCTACGA 
ATTGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGG AGGGTGGCAT CCCTGCACCA GGGGCGGCCC CAGGAGGGCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCCTGAAG GGAGGGGTCT TGATTCAGCG GAGCCCGCAG 
CTCTGCCACC AGGACACGAT TTTATGGAAG GACGTCTTCC ATAAGAACAA CCAGCTGGCC 
CTCACGCTGA TAGACACCAA CCGCTCTCGG GCCTGCCCAC CCTGTTCTCC AGCTTGTAAA 
GACGCCCACT GCTGGGGGGC CAGCTCCGGG GACTGTCAGA GCTTGACGCG GACTGTCTGT 
GCGGGGGGCT GTGCCCGCTG CAAGGGCCCA CAACCCACCG ACTGCTGCCA CGAGCAGTGT 
GCTGCTGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTTCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACGGA CACCTTCGAA 
TCCATGCCCA ACCCTGAGGG CCGATATACC TTCGGGGCCA GCTGTGTGAC CTCCTGTCCC 
TACAACTACC TGTCTACGGA TGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACGG CTGAGGATGG GACACAGCGG TGCGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GTCTGGGCAT GGAGCACCTG CGGGAGGTGA GAGCGGTCAC CAGTGCGAAC 
ATCCAGGAGT TTGCCGGCTG CAAGAAGATC TTTGGAAGCC TGGCATTTTT GCCAGAGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTACAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATCAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCCTGCCT 
AACCTCAGTG TCTTCCAGAA CCTGCGAGTA ATCCGGGGAC GAGTTCTGCA TGATGGTGCC 
TACTCGCTGA CCCTGCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAA 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACGCCCGCC TTTGCTTCGT GCACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCATAGTGC CAACCGGCCA 
GAGGAGGAGT GCGTGGGCGA GGGCCTGGCC TGCTACCCGC TGTGCGCCCA TGGGCACTGC 
TGGGGTCCAG GGCCGACCCA GTGCGTCAAC TGCAGCCAAT TCCTTCGGGG CCAGGAGTGC 
GTGGAAGAAT GCCGAGTACT GCAGGGGCTG CCCCGAGAGT ATGTGAAGGA CAGGTACTGT 
CTGCCGTGCC ACTCAGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT CGGATCGGAG 
GCTGACCAGT GTGTGGCCTG CGCCCACTAC AAGGACCCTC CCTTCTGTGT GGCTCGCTGC 
CCCAGTGGTG TGAAACCTGA CCTGTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACTTGCC AGCCGTGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGTCCCG CCGAGCAGAG AGCCAGCCCT GTGACATCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG CTGTGGTCGT GGGGCTGGTC CTCGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACTAT GCGGAGGCTG CTGCAGGAAA CCGAGCTGGT GGAGCCGCTG 
ACGCCTAGTG GAGCGATGCC CAACCAGGCT CAGATGCGGA TCCTGAAAGA GACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACAG TCTACAAGGG CATCTGGATC 
CCTGATGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAACACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCATATGTGA TGGCTGGAGT GGGCTCCCCG 
TATGTGTCCC GCCTCCTGGG CATCTGCCTG ACATCCACGG TGCAGCTGGT GACACAGCTT 
ATGCCCTACG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT GGGCTCCCAG 
GACTTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTCCGG 
CTGGTGCACA GGGACCTGGC TGCCCGGAAT GTGCTGGTCA AGAGTCCCAA CCATGTCAAG 
ATTACAGATT TCGGGCTGGC TCGGTTGCTG GACATCGACG AGACAGAGTA CCATGCGGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCC TTCTCCGCCG GCGGTTCACC 
CACCAGAGTG ATGTGTGGAG CTATGGTGTG ACTGTGTGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATCCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA GTGCTGGATG 
ATAGACTCTG AATGCCGACC CCGGTTCCGG GAGTTGGTGG CCGAATTCTC ACGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATTCAG AATGAAGACT TGGGCCCCGC CAGCCCCTTG 
GACAGCACCT TCTACCGTTC ACTACTGGAA GATGATGACA TGGGGGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG AACCTACCCC AGGGGCTGGG 
GGCACTGCCC ACCGACGGCA CCGCAGCTCA TCCACCAGGG TCAGTGTCCT CTGTCACACT 
GAGAGTGGCG GTGGTGAGCT GACTCTAGGA CTGGAGCCCT CCGAGGAGGA GCCCCCCAAG 
TCTCCACTGG CACCCTCAGA GGGCGCTGGC TCTGACGTGT TTGATGGTGA CTTGGGAATG 
GGGGCAGCCA AGGGGCTGCA GAGCCTTCCC TCACAGGACC CCAGCCCTCT CCAGCGGTAC 
AGTGAGGACC CTACGGTACC CTTGCCCCCT GAGACTGATG GCTACGTCGC CCCCCTGACC 
TGCAGCCCCC AGCCTGAATA TGTGAACCAG CCAGAAGTTT GGCCGCAGCC CCCCTCGCCC 
CTAGAAGGCC CTCTGCCTCC TTCCCGACCG GCTGGTGCCA CTCTGGAAAG GCCCAAGACT 
CTGTCCCCCA AGACTCTCTC CCCTGGCAAG AATGGGGTTG TCAAAGACGT TTTTGCCTTT 
GGGAGTGCTG TGGAGAATCC GGAGTACCTG GCACCCCGGG GCAGAGCTGC CCCTCAGCCC 
CACCCTCCTC CAGCCTTCAG CCCAGCCTTT GACAACCTGT ATTACTGGGA CCAGGATCCA 
TCAGAGCGGG GCTCTCCACC CAGCACCTTT GAAGGGACCC CTACAGCAGA GAACCCGGAG 
TACCTGGGGC TGGACGTGCC AGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HER-2 and EGFR mRNA Expression and Its Relationship with Versican in Malignant Matrix-Producing Tumors of the Canine Mammary Gland.
PloS one11(8)e0160419(2016)
Damasceno KA,Ferreira E,Estrela-Lima A,Gamba Cde O,Miranda FF,Alves MR,Rocha RM,de Barros AL,Cassali GD

Investigation of HER2 expression in canine mammary tumors by antibody-based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer?
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine36(11)9083-91(2015 Nov)
Burrai GP,Tanca A,De Miglio MR,Abbondio M,Pisanu S,Polinas M,Pirino S,Mohammed SI,Uzzau S,Addis MF,Antuofermo E

Molecular phenotype of primary mammary tumours and distant metastases in female dogs and cats.
Journal of comparative pathology150(2-3)194-7(2014 Feb-Apr)
Beha G,Muscatello LV,Brunetti B,Asproni P,Millanta F,Poli A,Benazzi C,Sarli G

HER-2 expression in canine morphologically normal, hyperplastic and neoplastic mammary tissues and its correlation with the clinical outcome.
Research in veterinary science94(2)299-305(2013 Apr)
Ressel L,Puleio R,Loria GR,Vannozzi I,Millanta F,Caracappa S,Poli A

Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.
The Journal of biological chemistry284(4)2080-7(2009 Jan)
Gordon LI,Burke MA,Singh AT,Prachand S,Lieberman ED,Sun L,Naik TJ,Prasad SV,Ardehali H

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ERBB2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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