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  • gene symbol (e.g. TP53)
  • gene name (e.g. tumor protein p53)
  • gene synonyms (e.g. FLJ92943)
  • Ensembl ID (e.g. ENSG0000141510)
  • Accession No. (e.g. NM_000546)
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Xenopus tropicalis (tropical clawed frog)


Activation of the AP-1 family of transcription factors Toll Like Receptor 9 (TLR9) Cascade
Activated TLR4 signalling MyD88:Mal cascade initiated on plasma membrane
Initial triggering of complement Negative regulators of RIG-I/MDA5 signaling
STAT6-mediated induction of chemokines Fc epsilon receptor (FCERI) signaling
CD209 (DC-SIGN) signaling Regulation of signaling by CBL
Lysosome Vesicle Biogenesis Gap junction trafficking
Gap junction assembly Oligomerization of connexins into connexons
Formation of annular gap junctions c-src mediated regulation of Cx43 function and closure of gap junctions
Endosomal Sorting Complex Required For Transport (ESCRT) Translocation of GLUT4 to the plasma membrane
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Nephrin interactions
Hemostasis Elevation of cytosolic Ca2+ levels
Reduction of cytosolic Ca++ levels ADP signalling through P2Y purinoceptor 12
ADP signalling through P2Y purinoceptor 1 Platelet Aggregation (Plug Formation)
Disinhibition of SNARE formation Formation of Fibrin Clot (Clotting Cascade)
Dissolution of Fibrin Clot Base-Excision Repair, AP Site Formation
Depurination Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
DNA Double-Strand Break Repair Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Metabolism of carbohydrates Fructose metabolism
Glycosaminoglycan metabolism Antimicrobial peptides
Signaling by MET MET activates PI3K/AKT signaling
MET activates PTPN11 MET activates RAP1 and RAC1
RAB GEFs exchange GTP for GDP on RABs Formation of the cornified envelope
HDMs demethylate histones RMTs methylate histone arginines
Cellular responses to stress Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha
Cellular Senescence Macroautophagy
Generic Transcription Pathway YAP1- and WWTR1 (TAZ)-stimulated gene expression
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
TP53 Regulates Transcription of DNA Repair Genes Regulation of TP53 Expression and Degradation
RNA Polymerase I Promoter Clearance RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Transcription Termination
mRNA Splicing - Minor Pathway SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Processing of Intronless Pre-mRNAs Mitochondrial tRNA aminoacylation
mRNA decay by 3' to 5' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Small interfering RNA (siRNA) biogenesis Regulation of mRNA stability by proteins that bind AU-rich elements
Formation of the ternary complex, and subsequently, the 43S complex Recycling of eIF2:GDP
Eukaryotic Translation Elongation Metabolism of non-coding RNA
Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Negative epigenetic regulation of rRNA expression Syndecan interactions
Collagen degradation Mitochondrial biogenesis
Transcriptional activation of mitochondrial biogenesis Mitochondrial translation elongation
Anchoring of the basal body to the plasma membrane Chaperonin-mediated protein folding
Gamma carboxylation, hypusine formation and arylsulfatase activation Synthesis of GDP-mannose
ER Quality Control Compartment (ERQC) COPII (Coat Protein 2) Mediated Vesicle Transport
Reactions specific to the complex N-glycan synthesis pathway N-Glycan antennae elongation
Processing and activation of SUMO SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMOylation of transcription factors Incretin synthesis, secretion, and inactivation
Peptide hormone biosynthesis IRE1alpha activates chaperones
Programmed Cell Death Regulation by c-FLIP
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