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Drosophila melanogaster (fruit fly)


RNA Polymerase III Transcription Initiation RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Transcription Elongation Processing of Intronless Pre-mRNAs
Cytosolic tRNA aminoacylation mRNA decay by 3' to 5' exoribonuclease
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Gene Silencing by RNA
RNA polymerase II transcribes snRNA genes Depurination
Resolution of Abasic Sites (AP sites) DNA Damage Bypass
Recognition of DNA damage by PCNA-containing replication complex Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
Translesion synthesis by REV1 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Homologous DNA Pairing and Strand Exchange Resolution of D-Loop Structures
Global Genome Nucleotide Excision Repair (GG-NER) Mismatch Repair
Cell Cycle Checkpoints G1/S DNA Damage Checkpoints
p53-Independent G1/S DNA damage checkpoint G2/M DNA damage checkpoint
G2/M DNA replication checkpoint Mitotic Spindle Checkpoint
Inactivation of APC/C via direct inhibition of the APC/C complex G1/S-Specific Transcription
E2F-enabled inhibition of pre-replication complex formation S Phase
Establishment of Sister Chromatid Cohesion G2/M Transition
Depolymerisation of the Nuclear Lamina Mitotic Metaphase and Anaphase
Separation of Sister Chromatids APC/C:Cdc20 mediated degradation of mitotic proteins
Metabolism Glucose transport
Transport and synthesis of PAPS Keratan sulfate biosynthesis
Synthesis of IP2, IP, and Ins in the cytosol Trafficking of dietary sterols
Mitochondrial Fatty Acid Beta-Oxidation Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Ketone body metabolism Peroxisomal lipid metabolism
Plasmalogen biosynthesis Cholesterol biosynthesis
Acyl chain remodelling of PG Synthesis of CL
Synthesis of PIPs at the plasma membrane alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Linoleic acid (LA) metabolism Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Adrenaline,noradrenaline inhibits insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
PKA activation in glucagon signalling Pyruvate metabolism
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
The fatty acid cycling model Purine ribonucleoside monophosphate biosynthesis
Pyrimidine biosynthesis Metabolism of vitamins and cofactors
Carnitine synthesis Lysine catabolism
Interconversion of polyamines Regulation of ornithine decarboxylase (ODC)
Urea cycle Serotonin and melatonin biosynthesis
Glycine degradation Sulfur amino acid metabolism
Selenoamino acid metabolism Phase 1 - Functionalization of compounds
Vitamins Formation of the active cofactor, UDP-glucuronate
Cytosolic sulfonation of small molecules Aflatoxin activation and detoxification
Phosphate bond hydrolysis by NTPDase proteins Pyrophosphate hydrolysis
GRB2 events in ERBB2 signaling Disassembly of the destruction complex and recruitment of AXIN to the membrane
Cargo recognition for clathrin-mediated endocytosis Negative regulation of activity of TFAP2 (AP-2) family transcription factors
O-linked glycosylation of mucins UCH proteinases
Ub-specific processing proteases MET activates PI3K/AKT signaling
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Antimicrobial peptides
Metal sequestration by antimicrobial proteins TFAP2 (AP-2) family regulates transcription of cell cycle factors
GRB7 events in ERBB2 signaling Interleukin-10 signaling
Apoptotic cleavage of cellular proteins Caspase-mediated cleavage of cytoskeletal proteins
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