Homo sapiens (human) Signaling by VEGF (provided by Reactome)
About the Signaling by VEGF pathway
In normal development vascular endothelial growth factors (VEGFs) are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis).
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
321 gene
Gene Symbol | Full Name |
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ACTN2 | actinin, alpha 2 |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
ANGPT1 | angiopoietin 1 |
ARAF | A-Raf proto-oncogene, serine/threonine kinase |
RHOA | ras homolog family member A |
ARRB1 | arrestin, beta 1 |
ARRB2 | arrestin, beta 2 |
AXL | AXL receptor tyrosine kinase |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
BTC | betacellulin |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
CAMK2D | calcium/calmodulin-dependent protein kinase II delta |
CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CDC42 | cell division cycle 42 |
CDH5 | cadherin 5, type 2 (vascular endothelium) |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
MAPK14 | mitogen-activated protein kinase 14 |
CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
CSK | c-src tyrosine kinase |
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
CTNND1 | catenin (cadherin-associated protein), delta 1 |
CYBA | cytochrome b-245, alpha polypeptide |
CYBB | cytochrome b-245, beta polypeptide |
DLG4 | discs, large homolog 4 (Drosophila) |
DOCK1 | dedicator of cytokinesis 1 |
HBEGF | heparin-binding EGF-like growth factor |
DUSP1 | dual specificity phosphatase 1 |
DUSP2 | dual specificity phosphatase 2 |
DUSP4 | dual specificity phosphatase 4 |
DUSP5 | dual specificity phosphatase 5 |
DUSP6 | dual specificity phosphatase 6 |
DUSP7 | dual specificity phosphatase 7 |
DUSP8 | dual specificity phosphatase 8 |
DUSP9 | dual specificity phosphatase 9 |
EGF | epidermal growth factor |
EGFR | epidermal growth factor receptor |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
ERBB4 | erb-b2 receptor tyrosine kinase 4 |
EREG | epiregulin |
PTK2B | protein tyrosine kinase 2 beta |
FGA | fibrinogen alpha chain |
FGB | fibrinogen beta chain |
FGF1 | fibroblast growth factor 1 (acidic) |
FGF2 | fibroblast growth factor 2 (basic) |
FGF3 | fibroblast growth factor 3 |
FGF4 | fibroblast growth factor 4 |
FGF5 | fibroblast growth factor 5 |
FGF6 | fibroblast growth factor 6 |
FGF7 | fibroblast growth factor 7 |
FGF8 | fibroblast growth factor 8 (androgen-induced) |
FGF9 | fibroblast growth factor 9 |
FGF10 | fibroblast growth factor 10 |
FGFR1 | fibroblast growth factor receptor 1 |
FGFR3 | fibroblast growth factor receptor 3 |
FGFR2 | fibroblast growth factor receptor 2 |
FGFR4 | fibroblast growth factor receptor 4 |
FGG | fibrinogen gamma chain |
FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
FLT1 | fms-related tyrosine kinase 1 |
FLT4 | fms-related tyrosine kinase 4 |
FN1 | fibronectin 1 |
MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
GRB2 | growth factor receptor-bound protein 2 |
GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
NCKAP1L | NCK-associated protein 1-like |
NRG1 | neuregulin 1 |
HRAS | Harvey rat sarcoma viral oncogene homolog |
HSPB1 | heat shock 27kDa protein 1 |
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
IL2 | interleukin 2 |
IL2RA | interleukin 2 receptor, alpha |
IL2RB | interleukin 2 receptor, beta |
IL2RG | interleukin 2 receptor, gamma |
IL3 | interleukin 3 |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
IL5 | interleukin 5 |
IL5RA | interleukin 5 receptor, alpha |
IRS1 | insulin receptor substrate 1 |
ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
ITGAV | integrin, alpha V |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
JAK1 | Janus kinase 1 |