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Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism
Authors: Zhuang N, Zhang H, Li L, Wu X, Yang C, Zhang Y.
Journal: J Biol Chem
PubMed ID: 31914412
Products & Services: Gene Synthesis   
Thioredoxin Reductase 1 Is a Highly Immunogenic Cell Surface Antigen in Paracoccidioides spp, Candida albicans, and Cryptococcus neoformans
Authors: de Oliveira FFM, Paredes V, de Sousa HR, D'Áurea Moura ÁN, Riasco-Palacios J, Casadevall A, Felipe MSS, Nicola AM, , .
Journal: Front Microbiol
PubMed ID: 31993026
Doi: 10.3389/fmicb.2019.02930
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1H, 13C, 15 N chemical shift assignments of the FKBP12 protein from the pathogenic fungi Candida auris and Candida glabrata
Authors: Bashir Q, LeMaster DM, Hernández G.
Journal: Biomol NMR Assign
PubMed ID: 31950462
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Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast
Authors: Pollo-Oliveira L, Klassen R, Davis N, Ciftci A, Bacusmo JM, Martinelli M, DeMott MS, Begley TJ, Dedon PC, Schaffrath R, de Crécy-Lagard V, .
Journal: Biomolecules
PubMed ID: 32085421
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One-Year Old Dormant, "Non-culturable" Mycobacterium tuberculosis Preserves Significantly Diverse Protein Profile
Authors: Trutneva KA, Shleeva MO, Demina GR, Vostroknutova GN, Kaprelyans AS.
Journal: Front Cell Infect Microbiol
PubMed ID: 32117801
Doi: 10.3389/fcimb.2020.00026
Products & Services: Catalog Antibody   
Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1
Authors: Loring HS, Icso JD, Nemmara VV, Thompson PR, .
Journal: Biochemistry
PubMed ID: 32049506
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Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors
Authors: Hasbi A, Nguyen T, Rahal H, Manduca JD, Miksys S, Tyndale RF, , Madras BK, Perreault ML, George SR, .
Journal: Biol Sex Differ
PubMed ID: 32087746
Doi: 10.1186/s13293-020-00285-9
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Resistance Evolution Against Antimicrobial Peptides in Staphylococcus aureus Alters Pharmacodynamics Beyond the MIC
Authors: El Shazely B, Yu G, Johnston PR, , Rolff J, .
Journal: Front Microbiol
PubMed ID: 32117132
Doi: 10.3389/fmicb.2020.00103
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Modulating the Stiffness of the Myosin VI Single α-Helical Domain
Authors: Barnes CA, Shen Y, Ying J, Bax A.
Journal: Biophys J
PubMed ID: 32049057
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Characterisation of insoluble α-1,3-/α-1,6 mixed linkage glucan produced in addition to soluble α-1,6-linked dextran by glucansucrase (DEX-N) from Leuconostoc citreum ABK-1
Authors: Wangpaiboon K, Waiyaseesang N, Panpetch P, Charoenwongpaiboon T, Nepogodiev SA, Ekgasit S, Field RA, Pichayangkura R.
Journal: Int J Biol Macromol
PubMed ID: 32097735
Products & Services: Gene Synthesis   
Distribution of Neoehrlichia mikurensis in Ixodes ricinus ticks along the coast of Norway: The western seaboard is a low-prevalence region
Authors: Pedersen BN, Jenkins A, Paulsen KM, Okbaldet YB, Edgar KS, Lamsal A, Soleng A, Andreassen ÅK.
Journal: Zoonoses Public Health
PubMed ID: 31705635
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Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium
Authors: Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EY, Loh YE, Ding J, Shen L, Xu PX, .
Journal: Nucleic Acids Res
PubMed ID: 31956913
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Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab
Authors: Farràs M, Román R, Camps M, Miret J, Martínez Ó, Pujol X, Casablancas A, Cairó JJ.
Journal: BMC Mol Cell Biol
PubMed ID: 31964343
Doi: 10.1186/s12860-019-0244-x
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TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis
Authors: Niederkorn M, Hueneman K, Choi K, Varney ME, Romano L, Pujato MA, Greis KD, Inoue JI, Meetei R, Starczynowski DT.
Journal: Cell Rep
PubMed ID: 32101751
Doi: 10.1016/j.celrep.2020.01.093
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Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen
Authors: Ou L, Kong WP, Chuang GY, Ghosh M, Gulla K, O'Dell S, Varriale J, Barefoot N, Changela A, Chao CW, Cheng C, Druz A, Kong R, McKee K, Rawi R, Sarfo EK, Schön A, Shaddeau A, Tsybovsky Y, Verardi R, Wang S, Wanninger TG, Xu K, Yang GJ, Zhang B, Zhang Y, Zhou T; VRC Production Program, Arnold FJ, Doria-Rose NA, Lei QP, Ryan ET, Vann WF, Mascola JR, Kwong PD.
Journal: Sci Rep
PubMed ID: 32080235
Doi: 10.1038/s41598-020-59711-y
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Spatially remote motifs cooperatively affect substrate preference of a ruminal GH26-type endo-β-1,4-mannanase
Authors: Mandelli F, de Morais MAB, de Lima EA, Oliveira L, Persinoti GF, Murakami MT.
Journal: J Biol Chem
PubMed ID: 32139511
Doi: 10.1074/jbc.RA120.012583
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Use of chimeric antigen receptor NK-92 cells to target mesothelin in ovarian cancer
Authors: Cao B, Liu M, Wang L, Liang B, Feng Y, Chen X, Shi Y, Zhang J, Ye X, Tian Y, Zhi C, Li J, Lian H, Wu Q, Zhang Z.
Journal: Biochem Biophys Res Commun
PubMed ID: 31980173
Doi: 10.1016/j.bbrc.2020.01.053
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Multienzyme detection and in-situ monitoring of enzyme activity by bending CE using quantum dots-based polypeptide substrate
Authors: Qiu L, Cui P, Zhu Z, Xu M, Jia W, Sheng J, Ni X, Zhou S, Wang J, .
Journal: Electrophoresis
PubMed ID: 32091140
Doi: 10.1002/elps.202000023
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Eomes broadens the scope of CD8 T-cell memory by inhibiting apoptosis in cells of low affinity
Authors: Kavazović I, Han H, Balzaretti G, Slinger E, Lemmermann NAW, Ten Brinke A, Merkler D, Koster J, Bryceson YT, de Vries N, Jonjić S, Klarenbeek PL, Polić B, Eldering E, Wensveen FM, .
Journal: PLoS Biol
PubMed ID: 32182234
Doi: 10.1371/journal.pbio.3000648
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Serological evidence of exposure to ebolaviruses in domestic pigs from Guinea
Authors: Fischer K, Camara A, Troupin C, Fehling SK, Strecker T, Groschup MH, Tordo N, Diederich S.
Journal: Transbound Emerg Dis
PubMed ID: 31627257
Doi: 10.1111/tbed.13391
Products & Services: Catalog Antibody   
Site-Specific Post-translational Surface Modification of Adeno-Associated Virus Vectors Using Leucine Zippers
Authors: Thadani NN, Yang J, Moyo B, Lee CM, Chen MY, Bao G, Suh J, , .
Journal: ACS Synth Biol
PubMed ID: 32068391
Doi: 10.1021/acssynbio.9b00341
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In vitro assays for effector T cell functions and activity of immunomodulatory antibodies
Authors: Zappasodi R, Budhu S, Abu-Akeel M, Merghoub T.
Journal: Methods Enzymol
PubMed ID: 31948562
Doi: 10.1016/bs.mie.2019.08.012
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Peptide Disc Mediated Control of Membrane Protein Orientation in Supported Lipid Bilayers for Surface-Sensitive Investigations
Authors: Luchini A, Tidemand FG, Johansen NT, Campana M, Sotres J, Ploug M, Cárdenas M, Arleth L.
Journal: Anal Chem
PubMed ID: 31769649
Doi: 10.1021/acs.analchem.9b04125
Products & Services: Molecular Biology Reagents   
Exploration of Missing Proteins by a Combination Approach to Enrich the Low-Abundance Hydrophobic Proteins from Four Cancer Cell Lines
Authors: Zhang Y, Lin Z, Tan Y, Bu F, Hao P, Zhang K, Yang H, Liu S, Ren Y, .
Journal: J Proteome Res
PubMed ID: 31773964
Doi: 10.1021/acs.jproteome.9b00590
Products & Services: Peptide Synthesis   
NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance
Authors: Pak JS, DeLoughery ZJ, Wang J, Acharya N, Park Y, Jaworski A, Özkan E, .
Journal: Nat Commun
PubMed ID: 32198364
Doi: 10.1038/s41467-020-15211-1
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The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis
Authors: Gómez-Fernández P, Lopez de Lapuente Portilla A, Astobiza I, Mena J, Urtasun A, Altmann V, Matesanz F, Otaegui D, Urcelay E, Antigüedad A, Malhotra S, Montalban X, Castillo-Triviño T, Espino-Paisán L, Aktas O, Buttmann M, Chan A, Fontaine B, Gourraud PA, Hecker M, Hoffjan S, Kubisch C, Kümpfel T, Luessi F, Zettl UK, Zipp F, Alloza I, Comabella M, Lill CM, , Vandenbroeck K, .
Journal: Cells
PubMed ID: 31936765
Doi: 10.3390/cells9010175
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Structure and mechanism of the ER-based glucosyltransferase ALG6
Authors: Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP.
Journal: nature
PubMed ID: 32103179
Doi: 10.1038/s41586-020-2044-z
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Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation
Authors: Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B.
Journal: Sci Immunol
PubMed ID: 31980486
Doi: 10.1126/sciimmunol.aaz0085
Products & Services: Recombinant Proteins   
Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics
Authors: Horns F, Dekker CL, Quake SR.
Journal: Cell Rep
PubMed ID: 31968262
Doi: 10.1016/j.celrep.2019.12.063
Products & Services: Recombinant Proteins   
CAMIO: a transgenic CRISPR pipeline to create diverse targeted genome deletions in Drosophila
Authors: Chen HM, Marques JG, Sugino K, Wei D, Miyares RL, Lee T.
Journal: Nucleic Acids Res
PubMed ID: 32187363
Doi: 10.1093/nar/gkaa177
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Engineered Stem Cells Improve Neurogenic Bladder by Overexpressing SDF-1 in a Pelvic Nerve Injury Rat Model
Authors: Zhu GQ, Jeon SH, Lee KW, Cho HJ, Ha US, Hong SH, Lee JY, Kwon EB, Kim HJ, Lee SM, Kim HY, Kim SW, Bae WJ, .
Journal: Cell Transplant
PubMed ID: 32067480
Doi: 10.1177/0963689720902466
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Computer-guided library generation applied to the optimization of single-domain antibodies
Authors: Akiba H, Tamura H, Caaveiro JMM, Tsumoto K, , .
Journal: Protein Eng Des Sel
PubMed ID: 32167147
Doi: 10.1093/protein/gzaa006
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Downregulation of transcription factor TCTP elevates microRNA-200a expression to restrain Myt1L expression, thereby improving neurobehavior and oxidative stress injury in cerebral palsy rats
Authors: He X, Liu Z, Pang Y, Xu W, Zhao L, Li H.
Journal: Cell Cycle
PubMed ID: 32174219
Doi: 10.1080/15384101.2020.1717044
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Characterization and Control of Dynamic Rearrangement in a Self-Assembled Antibody Carrier
Authors: Dhankher A, Hernandez ME, Howard HC, Champion JA.
Journal: Biomacromolecules
PubMed ID: 32134251
Doi: 10.1021/acs.biomac.9b01712
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PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter
Authors: Xu X, Zhou Y, , Fu B, Zhang J, Dong Z, Zhang X, Shen N, Sun R, Tian Z, Wei H, .
Journal: FASEB J
PubMed ID: 32190943
Doi: 10.1096/fj.202000121R
Botrytis cinerea induces local hypoxia in Arabidopsis leaves
Authors: Valeri MC, Novi G, Weits DA, Mensuali A, Perata P, Loreti E.
Journal: New Phytol
PubMed ID: 32124454
Doi: 10.1111/nph.16513
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Up-regulated microRNA-411 or declined RIPK1 inhibits proliferation and promotes apoptosis of synoviocytes in rheumatoid arthritis mice via decreased NF-κB pathway
Authors: Huang Y, Chen K, Yu H, Chen D, Deng L, Zhang Y, Xue X, Pan X, .
Journal: Cell Cycle
PubMed ID: 32116107
Doi: 10.1080/15384101.2020.1717033
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The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia
Authors: Machado MG, Tavares LP, Souza GVS, Queiroz-Junior CM, Ascenção FR, Lopes ME, Garcia CC, Menezes GB, Perretti M, Russo RC, Teixeira MM, Sousa LP, .
Journal: FASEB J
PubMed ID: 31908042
Doi: 10.1096/fj.201902172R
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Regulating vitamin B12 biosynthesis via the cbiMCbl riboswitch in Propionibacterium strain UF1
Authors: Li J, Ge Y, Zadeh M, Curtiss R rd, Mohamadzadeh M, .
Journal: Proc Natl Acad Sci U S A
PubMed ID: 31836694
Doi: 10.1073/pnas.1916576116
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ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface
Authors: Yang J, LeBlanc ME, Cano I, Saez-Torres KL, Saint-Geniez M, Ng YS, D'Amore PA.
Journal: J Biol Chem
PubMed ID: 32193206
Doi: 10.1074/jbc.RA119.011192
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Process Characterization and Biophysical Analysis for a Yeast-Expressed Phlebotomus papatasi Salivary Protein (PpSP15) as a Leishmania Vaccine Candidate
Authors: Chen WH, Nyon MP, Poongavanam MV, Liu Z, Biter AB, Kundu RT, Strych U, Hotez PJ, Bottazzi ME.
Journal: J Pharm Sci
PubMed ID: 32070701
Doi: 10.1016/j.xphs.2020.02.004
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Frataxin deficiency in Friedreich's ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival
Authors: Tiano F, Amati F, Cherubini F, Morini E, Vancheri C, Maletta S, Fortuni S, Serio D, Quatrana A, Luffarelli R, Benini M, Alfedi G, Panarello L, Rufini A, Toschi N, Frontali M, Romano S, Marcotulli C, Casali C, Gioiosa S, Mariotti C, Mongelli A, Fichera M, Condò I, Novelli G, Testi R, Malisan F.
Journal: Hum Mol Genet
PubMed ID: 31943004
Doi: 10.1093/hmg/ddz306
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Mitotic slippage is determined by p31comet and the weakening of the spindle-assembly checkpoint
Authors: Lok TM, Wang Y, Xu WK, Xie S, Ma HT, Poon RYC.
Journal: Oncogene
PubMed ID: 32029899
Doi: 10.1038/s41388-020-1187-6
Products & Services: Peptide Synthesis   
Cell-Based Ligand Discovery for the ENL YEATS Domain
Authors: Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton EN, Young TS, Hull MV, Cravatt BF, Erb MA.
Journal: ACS Chem Biol
PubMed ID: 32176478
Doi: 10.1021/acschembio.0c00124
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Sequence and structural determinants of ligand-dependent alternating access of a MATE transporter
Authors: Jagessar KL, Claxton DP, Stein RA, Mchaourab HS.
Journal: Proc Natl Acad Sci U S A
PubMed ID: 32075917
Doi: 10.1073/pnas.1917139117
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In Silico Guided Discovery of Novel Class I and II Trypanosoma cruzi Epitopes Recognized by T Cells from Chagas' Disease Patients
Authors: Acevedo GR, Juiz NA, Ziblat A, Pérez Perri L, Girard MC, Ossowski MS, Fernández M, Hernández Y, Chadi R, Wittig M, Franke A, Nielsen M, Gómez KA.
Journal: J Immunol
PubMed ID: 32060134
Doi: 10.4049/jimmunol.1900873
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Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2
Authors: Solà-Riera C, García M, Ljunggren HG, Klingström J.
Journal: PLoS Pathog
PubMed ID: 32032391
Doi: 10.1371/journal.ppat.1008297
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Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates
Authors: Ouyang W, Guo P, Takeda K, Fu Q, Fang H, Frucht DM.
Journal: Proc Natl Acad Sci U S A
PubMed ID: 32041890
Doi: 10.1073/pnas.1913698117
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High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation
Authors: Dian C, Pérez-Dorado I, , Rivière F, Asensio T, Legrand P, Ritzefeld M, Shen M, Cota E, Meinnel T, Tate EW, Giglione C.
Journal: Nat Commun
PubMed ID: 32111831
Doi: 10.1038/s41467-020-14847-3
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Nucleobase mutants of a bacterial preQ1-II riboswitch that uncouple metabolite sensing from gene regulation
Authors: Dutta D, Wedekind JE.
Journal: J Biol Chem
PubMed ID: 31659117
Doi: 10.1074/jbc.RA119.010755
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