MicroRNAs in cancer
Homo sapiens (human) MicroRNAs in cancer (provided by KEGG)
About the MicroRNAs in cancer pathway
MicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein translation. Using high-throughput profiling, dysregulation of miRNAs has been widely observed in different stages of cancer.
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
297 gene
| Gene Symbol | Full Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| APC | adenomatous polyposis coli |
| RHOA | ras homolog family member A |
| ATM | ATM serine/threonine kinase |
| BAK1 | BCL2-antagonist/killer 1 |
| CCND1 | cyclin D1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL2L2 | BCL2-like 2 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| BRCA1 | breast cancer 1, early onset |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCND2 | cyclin D2 |
| CCNE1 | cyclin E1 |
| CCNG1 | cyclin G1 |
| CD44 | CD44 molecule (Indian blood group) |
| CDC25A | cell division cycle 25A |
| CDC25B | cell division cycle 25B |
| CDC25C | cell division cycle 25C |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CREBBP | CREB binding protein |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| E2F1 | E2F transcription factor 1 |
| E2F2 | E2F transcription factor 2 |
| E2F3 | E2F transcription factor 3 |
| EFNA3 | ephrin-A3 |
| EGFR | epidermal growth factor receptor |
| EP300 | E1A binding protein p300 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FGFR3 | fibroblast growth factor receptor 3 |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| GLS | glutaminase |
| GRB2 | growth factor receptor-bound protein 2 |
| HDAC1 | histone deacetylase 1 |
| HMOX1 | heme oxygenase 1 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K |
| HOXD10 | homeobox D10 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| TNC | tenascin C |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IRS1 | insulin receptor substrate 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| STMN1 | stathmin 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCL1 | myeloid cell leukemia 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MDM4 | MDM4, p53 regulator |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MMP9 | matrix metallopeptidase 9 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| NOTCH1 | notch 1 |
| NOTCH2 | notch 2 |
| NOTCH3 | notch 3 |
| NOTCH4 | notch 4 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLAU | plasminogen activator, urokinase |
| PLCG1 | phospholipase C, gamma 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PRKCA | protein kinase C, alpha |
| PRKCB | protein kinase C, beta |
| PRKCE | protein kinase C, epsilon |
| PRKCG | protein kinase C, gamma |
| MAPK1 | mitogen-activated protein kinase 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| PTEN | phosphatase and tensin homolog |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase |
| RDX | radixin |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
