MUTYH gene (MutY Homolog)
Do you need the MUTYH gene to express the MUTYH protein for functional or characterization studies? Get the MUTYH gene in an expression-ready vector for your molecular biology studies by ordering an MUTYH ORF clone.
About the MUTYH gene
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Genomic context of MUTYH gene
The human MUTYH gene is shown in the context of the human genome below. To see information about the MUTYH gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse MUTYH, rat MUTYH, and human MUTYH, as well as on-demand MUTYH ORF clones in 183 other species.
Genomic sequence of MUTYH gene
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