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Your can enter the following as search terms:

Entrez Gene ID (e.g. 7157)
gene symbol (e.g. TP53)
gene name (e.g. tumor protein p53)
gene synonyms (e.g. FLJ92943)
Ensembl ID (e.g. ENSG0000141510)
RefSeq Accession (e.g. NM_000546)

Species can be input after the keyword, using format "keyword [species:$species]" where $species can be name of species (like human or rat) or taxon id (like 9606).

Get more search, click here.

Where to target the version number? Example

GenScript

EGFR (Epidermal growth factor receptor) gene, Homo sapiens

Do you need expression-ready EGFR gene to study the functions and characteristics? GenScript offers EGFR gene in any custom vector for your molecular biology studies by ordering an EGFR ORF clone.

About the EGFR gene

EGFR protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Genomic context of EGFR gene

The human EGFR gene is shown in the context of the human genome below. To see information about the EGFR gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse EGFR, rat EGFR, and human EGFR, as well as on-demand EGFR ORF clones in other 183 species.

Chromosome 7 - NC_000007.14

Genomic sequence of EGFR gene

Learn more about EGFR gene

Bibliography

1.Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.
Vietsch EE, et al. Cancer Genet, 2017 Dec. PMID 29153095,

2.Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.
Blakely CM, et al. Nat Genet, 2017 Dec. PMID 29106415,

3.Prognostic implication of EGFR gene mutations and histological classification in patients with resected stage I lung adenocarcinoma.
Lin CY, et al. PLoS One, 2017. PMID 29065153,

4.Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter.
Greco ML, et al. Nucleic Acids Res, 2017 Sep 29. PMID 28973461

5.Clinical validation of a highly sensitive assay to detect EGFR mutations in plasma cell-free DNA from patients with advanced lung adenocarcinoma.
Li Y, et al. PLoS One, 2017. PMID 28829813,