Sh2d2a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sh2d2a
Entrez Gene ID	310688
Full Name	SH2 domain containing 2A
General protein information	Preferred Names SH2 domain containing 2A Names SH2 domain-containing protein 2A SH2 domain protein 2A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	T cell-specific SH3/SH2 adaptor protein; may be a transcriptional regulator; may be a marker for T cell proliferation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_207605.3	NP_997488.2	SH2 domain-containing protein 2A

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SH2D2A	XP_003434988.2
Homo sapiens (human)	SH2D2A	NP_003966.2
Bos taurus (cattle)	SH2D2A	NP_001098871.1
Pan troglodytes (chimpanzee)	SH2D2A	XP_001167540.1
Macaca mulatta (Rhesus monkey)	SH2D2A	XP_001116816.2
Rattus norvegicus (Norway rat)	Sh2d2a	NP_997488.2
Mus musculus (house mouse)	Sh2d2a	NP_067284.1

Gene Ontology
Bibliography

Related articles in PubMed

Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition.
Holmes K, Roberts OL, Thomas AM, Cross MJ
Cellular signalling19(10)2003-12(2007 Oct)

Regulation of cellular functions by the ERK5 signalling pathway.
Wang X, Tournier C
Cellular signalling18(6)753-60(2006 Jun)

cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells.
Nejad S, Bryceson Y, Dissen E, Sundvold-Gjerstad V, Naper C, Rolstad B, Spurkland A, Vaage JT
Immunogenetics56(5)338-42(2004 Aug)

Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene.
Smerdel A, Dai KZ, Lorentzen AR, Flatø B, Maslinski S, Thorsby E, Førre Ø, Spurkland A
Genes and immunity5(4)310-2(2004 Jun)

The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis.
Dai KZ, Harbo HF, Celius EG, Oturai A, Sørensen PS, Ryder LP, Datta P, Svejgaard A, Hillert J, Fredrikson S, Sandberg-Wollheim M, Laaksonen M, Myhr KM, Nyland H, Vartdal F, Spurkland A
Genes and immunity2(5)263-8(2001 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sh2d2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sh2d2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05606	NM_207605.3 Latest version!	Rattus norvegicus SH2 domain containing 2A (Sh2d2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sh2d2a ( NM_207605.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997488.2 Rattus norvegicus SH2 domain containing 2A (Sh2d2a), mRNA.

Price & Availability↑

CloneID	ORa05606
Clone ID Related Accession (Same CDS sequence)	NM_207605.3
Accession Version	NM_207605.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1527264000000
Organism	Rattus norvegicus(Norway rat)
Product	SH2 domain-containing protein 2A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC088087.1. On Jan 12, 2005 this sequence version replaced NM_207605.2. ##Evidence-Data-START## Transcript exon combination :: BC088087.1, AF468787.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689603, SAMEA2689605 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTTCT GCTTGGCCCA GACATGTCCC CAAGGGAATC ATGAAGCCAC CTCCCCAACC 
TTCAGCACCT TCCAGCCCAT GAACCTGACC CAGGGGAGAT GCCAGGACTT GGGTTGTGGG 
GGCAAGCCCA GCATGCAGGC TCTGAGGGAA CAGGAGGTTC AGCTCAGCCC CAGGGTCACC 
CACACGGTGG CCTCTGCCTC AGCCCCAGGA GCTGCCTGGG TCCTAGAGAG TGTCAACAGG 
GAGGAAGAGG AACCTGGGAA AGGTGAACTG TCATTGCAAG CTGAGACCAG AGCATGGGTT 
CAGAAGACCC AGGCCCACTG GCTCTTGCTC AGGACTGCCC CGCTTTGGTT CCATGGCTTC 
ATTACCAGAA GGGAAGCTGA GAGGCTACTG CAGTCCCAAC CTCTAGGATG CTATCTGGTG 
CGCTTCAGCG AGAGCGCTGT GACCTTCGTG CTGTCCTACA GGAGCCGAAC CTGCTGCCGT 
CACTTCCTCC TTGCTCAGCT AGGGGATGGG CGCCACGTGG TGCTGGGTGA AGACAGTGCC 
CACTCGCAGC TTCAGGACCT GCTTCAACAC TACACAGAGT GCCCCCTCAG CCCCTACGGG 
GAGATGCTCA CCCAACCCCT TGCTCGCCAG ACAGCTGAGC CTGCCGGTCT TTCCCTAAGG 
GGTGAATCAG ACTCTGGAAG CAGAAGACAG GACCCAGACA CCCAGCACAG CCTGTTCATC 
CAACAGGGGC AGGCCCATGC CCAGGCCCCA GGACATAAAG AGAAAGTGAG GGCCTCCCAA 
CAGAAGAAGA CTTCCCAGGC ATCCAGACCC AGGCCCCCCA TTCCTGCCAA GCCTCAGCTA 
CCTCTTGAAG TCTACACAAG TCCTGCTCCA CGACCTCATC AGGCCCTACC CATTAACCCC 
GTCTACCAGG AGCCTGATGA ACCCATAGCC TTCTATGCCA TGGGGCGGGG CAGCCCTGGG 
GATGCTCCTA GTAATATCTA TGCTGAGGTG GATGGCCCAC GGGAAATGCT ACCCATTGGG 
CACCCCACCC TCCATAAGTG CTGGTCCAGG CCTATCTCAG GAGGCCAGGG AAAGGGGGTA 
CAGGGAAAGA AAAGCTCAAG AAGGCCAGCA GGAAGAGGGA GCCCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997488.2
CDS	31..1161
Translation	MEFCLAQTCPQGNHEATSPTFSTFQPMNLTQGRCQDLGCGGKPSMQALREQEVQLSPRVTHTVASASAPGAAWVLESVNREEEEPGKGELSLQAETRAWVQKTQAHWLLLRTAPLWFHGFITRREAERLLQSQPLGCYLVRFSESAVTFVLSYRSRTCCRHFLLAQLGDGRHVVLGEDSAHSQLQDLLQHYTECPLSPYGEMLTQPLARQTAEPAGLSLRGESDSGSRRQDPDTQHSLFIQQGQAHAQAPGHKEKVRASQQKKTSQASRPRPPIPAKPQLPLEVYTSPAPRPHQALPINPVYQEPDEPIAFYAMGRGSPGDAPSNIYAEVDGPREMLPIGHPTLHKCWSRPISGGQGKGVQGKKSSRRPAGRGSPS

Target ORF information:

RefSeq Version	NM_207605.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus SH2 domain containing 2A (Sh2d2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207605.3

ORF Insert Sequence:

ATGGAGTTCT GCTTGGCCCA GACATGTCCC CAAGGGAATC ATGAAGCCAC CTCCCCAACC 
TTCAGCACCT TCCAGCCCAT GAACCTGACC CAGGGGAGAT GCCAGGACTT GGGTTGTGGG 
GGCAAGCCCA GCATGCAGGC TCTGAGGGAA CAGGAGGTTC AGCTCAGCCC CAGGGTCACC 
CACACGGTGG CCTCTGCCTC AGCCCCAGGA GCTGCCTGGG TCCTAGAGAG TGTCAACAGG 
GAGGAAGAGG AACCTGGGAA AGGTGAACTG TCATTGCAAG CTGAGACCAG AGCATGGGTT 
CAGAAGACCC AGGCCCACTG GCTCTTGCTC AGGACTGCCC CGCTTTGGTT CCATGGCTTC 
ATTACCAGAA GGGAAGCTGA GAGGCTACTG CAGTCCCAAC CTCTAGGATG CTATCTGGTG 
CGCTTCAGCG AGAGCGCTGT GACCTTCGTG CTGTCCTACA GGAGCCGAAC CTGCTGCCGT 
CACTTCCTCC TTGCTCAGCT AGGGGATGGG CGCCACGTGG TGCTGGGTGA AGACAGTGCC 
CACTCGCAGC TTCAGGACCT GCTTCAACAC TACACAGAGT GCCCCCTCAG CCCCTACGGG 
GAGATGCTCA CCCAACCCCT TGCTCGCCAG ACAGCTGAGC CTGCCGGTCT TTCCCTAAGG 
GGTGAATCAG ACTCTGGAAG CAGAAGACAG GACCCAGACA CCCAGCACAG CCTGTTCATC 
CAACAGGGGC AGGCCCATGC CCAGGCCCCA GGACATAAAG AGAAAGTGAG GGCCTCCCAA 
CAGAAGAAGA CTTCCCAGGC ATCCAGACCC AGGCCCCCCA TTCCTGCCAA GCCTCAGCTA 
CCTCTTGAAG TCTACACAAG TCCTGCTCCA CGACCTCATC AGGCCCTACC CATTAACCCC 
GTCTACCAGG AGCCTGATGA ACCCATAGCC TTCTATGCCA TGGGGCGGGG CAGCCCTGGG 
GATGCTCCTA GTAATATCTA TGCTGAGGTG GATGGCCCAC GGGAAATGCT ACCCATTGGG 
CACCCCACCC TCCATAAGTG CTGGTCCAGG CCTATCTCAG GAGGCCAGGG AAAGGGGGTA 
CAGGGAAAGA AAAGCTCAAG AAGGCCAGCA GGAAGAGGGA GCCCCTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition.
Cellular signalling19(10)2003-12(2007 Oct)
Holmes K,Roberts OL,Thomas AM,Cross MJ

Regulation of cellular functions by the ERK5 signalling pathway.
Cellular signalling18(6)753-60(2006 Jun)
Wang X,Tournier C

cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells.
Immunogenetics56(5)338-42(2004 Aug)
Nejad S,Bryceson Y,Dissen E,Sundvold-Gjerstad V,Naper C,Rolstad B,Spurkland A,Vaage JT

Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene.
Genes and immunity5(4)310-2(2004 Jun)
Smerdel A,Dai KZ,Lorentzen AR,Flatø B,Maslinski S,Thorsby E,Førre Ø,Spurkland A

The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis.
Genes and immunity2(5)263-8(2001 Aug)
Dai KZ,Harbo HF,Celius EG,Oturai A,Sørensen PS,Ryder LP,Datta P,Svejgaard A,Hillert J,Fredrikson S,Sandberg-Wollheim M,Laaksonen M,Myhr KM,Nyland H,Vartdal F,Spurkland A

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Sh2d2a cDNA ORF clone, Rattus norvegicus(Norway rat)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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