Grpca cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Grpca
Entrez Gene ID	192266
Full Name	glutamine/glutamic acid-rich protein A
Synonyms	Grp-Ca,Grpca_m
General protein information	Preferred Names glutamine/glutamic acid-rich protein A Names submandibular gland secretory Glx-rich protein CA glutamine/glutamic acid-rich protein A, mapped glutamine/glutamic acid-rich protein GRP-Ca
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q43
Summary	putative structural protein of tooth enamel [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_181440.1	NP_852105.1	submandibular gland secretory Glx-rich protein CA precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Chromosomal organization and expression analysis of two distinct genes encoding glutamine/glutamic acid-rich proteins.
Ten Hagen KG, Beres TM, Szpirer J, Szpirer C, Tabak LA
The Biochemical journal324 ( Pt 1)177-84(1997 May)

Characterization of the gene encoding the salivary Gln/Glu-rich C-terminal variant A protein.
Cooper LF, Tabak LA
Gene106(2)261-6(1991 Oct)

Secretagogue-coupled changes in the expression of glutamine/glutamic acid-rich proteins (GRPs). Isoproterenol induces changes in GRP transcript expression and changes in isoforms secreted.
Cooper LF, Elia DM, Tabak LA
The Journal of biological chemistry266(6)3532-9(1991 Feb)

Molecular characterization of glutamic acid/glutamine-rich secretory proteins from rat submandibular glands.
Mirels L, Bedi GS, Dickinson DP, Gross KW, Tabak LA
The Journal of biological chemistry262(15)7289-97(1987 May)

Genes encoding proteins with homologous contiguous repeat sequences are highly expressed in the serous cells of the rat submandibular gland.
Heinrich G, Habener JF
The Journal of biological chemistry262(11)5262-70(1987 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Grpca gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Grpca cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13409	NM_181440.1 Latest version!	Rattus norvegicus glutamine/glutamic acid-rich protein A (Grpca), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Grpca ( NM_181440.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_852105.1 Rattus norvegicus glutamine/glutamic acid-rich protein A (Grpca), mRNA.

Price & Availability↑

CloneID	ORa13409
Clone ID Related Accession (Same CDS sequence)	NM_181440.1
Accession Version	NM_181440.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577116800000
Organism	Rattus norvegicus(Norway rat)
Product	submandibular gland secretory Glx-rich protein CA precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M58654.1. On Apr 19, 2005 this sequence version replaced XM_579719.1. ##Evidence-Data-START## Transcript exon combination :: M58654.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTTGTGG TCCTGCTCAC AGCAGCCTTG CTGGCTCTGA GCTCAGCTCA GGGCACGGAT 
GAAGAGGTCA ACAATGCTGA GACCAGTGAT GTACCAGCAG ATTCTGAACA ACAACCCGTG 
GACTCGGGTT CAGATCCACC TTCTGCTGAT GCAGATGCAG AGAATGTTCA AGAGGGTGAA 
TCAGCCGCAC CAGCAAATGA AGAGCCTCCT GCCACCTCTG GGAGTGAAGA GGAACAGCAG 
CAGCAGGAAC CCACACAGGC AGAGAATCAA GAGCCTCCTG CCACCTCTGG GAGTGAAGAG 
GAACAGCAGC AGCAGGAACC CACACAGGCG GAGAATCAAG AGCCTCCTGC CACCTCTGGG 
AGTGAAGAGG AACAGCAGCA GCAGGAACCC ACACAGGCGG AGGATCAACA GCCTCCTGCC 
ACCTCTGGGA GTGAAGAGGA ACAGCAGCAG CAGGAATCCA CACAGGCAGA GAATCAAGAG 
CCTTCTGACT CTGCTGGGGA AGGACAGGAA ACTCAACCTG AGGAAGGAAA TGTAGAGTCA 
CCTCCCTCTT CTCCTGAAAA CTCACAAGAA CAACCACAGC AAACAAATCC AGAGGAGAAA 
CCGCCTGCTC CTAAGACTCA GGAAGAACCA CAGCACGATA GAGGTCGTCC TCCAAAGAAG 
ATTTTTCCTT TTTTCATTTA CAGAGGAAGA CCAGTAGTAG TATTCAGGCC TCGAAGCCTA 
GGAATCCATT CGCCAGAAGA TTTTAGAGAG TACCTGACAA GATTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_852105.1
CDS	33..800
Translation	MLVVLLTAALLALSSAQGTDEEVNNAETSDVPADSEQQPVDSGSDPPSADADAENVQEGESAAPANEEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQQQQEPTQAEDQQPPATSGSEEEQQQQESTQAENQEPSDSAGEGQETQPEEGNVESPPSSPENSQEQPQQTNPEEKPPAPKTQEEPQHDRGRPPKKIFPFFIYRGRPVVVFRPRSLGIHSPEDFREYLTRL

Target ORF information:

RefSeq Version	NM_181440.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutamine/glutamic acid-rich protein A (Grpca), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181440.1

ORF Insert Sequence:

ATGCTTGTGG TCCTGCTCAC AGCAGCCTTG CTGGCTCTGA GCTCAGCTCA GGGCACGGAT 
GAAGAGGTCA ACAATGCTGA GACCAGTGAT GTACCAGCAG ATTCTGAACA ACAACCCGTG 
GACTCGGGTT CAGATCCACC TTCTGCTGAT GCAGATGCAG AGAATGTTCA AGAGGGTGAA 
TCAGCCGCAC CAGCAAATGA AGAGCCTCCT GCCACCTCTG GGAGTGAAGA GGAACAGCAG 
CAGCAGGAAC CCACACAGGC AGAGAATCAA GAGCCTCCTG CCACCTCTGG GAGTGAAGAG 
GAACAGCAGC AGCAGGAACC CACACAGGCG GAGAATCAAG AGCCTCCTGC CACCTCTGGG 
AGTGAAGAGG AACAGCAGCA GCAGGAACCC ACACAGGCGG AGGATCAACA GCCTCCTGCC 
ACCTCTGGGA GTGAAGAGGA ACAGCAGCAG CAGGAATCCA CACAGGCAGA GAATCAAGAG 
CCTTCTGACT CTGCTGGGGA AGGACAGGAA ACTCAACCTG AGGAAGGAAA TGTAGAGTCA 
CCTCCCTCTT CTCCTGAAAA CTCACAAGAA CAACCACAGC AAACAAATCC AGAGGAGAAA 
CCGCCTGCTC CTAAGACTCA GGAAGAACCA CAGCACGATA GAGGTCGTCC TCCAAAGAAG 
ATTTTTCCTT TTTTCATTTA CAGAGGAAGA CCAGTAGTAG TATTCAGGCC TCGAAGCCTA 
GGAATCCATT CGCCAGAAGA TTTTAGAGAG TACCTGACAA GATTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromosomal organization and expression analysis of two distinct genes encoding glutamine/glutamic acid-rich proteins.
The Biochemical journal324 ( Pt 1)177-84(1997 May)
Ten Hagen KG,Beres TM,Szpirer J,Szpirer C,Tabak LA

Characterization of the gene encoding the salivary Gln/Glu-rich C-terminal variant A protein.
Gene106(2)261-6(1991 Oct)
Cooper LF,Tabak LA

Secretagogue-coupled changes in the expression of glutamine/glutamic acid-rich proteins (GRPs). Isoproterenol induces changes in GRP transcript expression and changes in isoforms secreted.
The Journal of biological chemistry266(6)3532-9(1991 Feb)
Cooper LF,Elia DM,Tabak LA

Molecular characterization of glutamic acid/glutamine-rich secretory proteins from rat submandibular glands.
The Journal of biological chemistry262(15)7289-97(1987 May)
Mirels L,Bedi GS,Dickinson DP,Gross KW,Tabak LA

Genes encoding proteins with homologous contiguous repeat sequences are highly expressed in the serous cells of the rat submandibular gland.
The Journal of biological chemistry262(11)5262-70(1987 Apr)
Heinrich G,Habener JF