| Gene Symbol | HYAL2 |
| Entrez Gene ID | 443154 |
| Full Name | hyaluronoglucosaminidase 2 |
| Synonyms | oHyal2 |
| Gene Type | protein-coding |
| Organism | Ovis aries(sheep) |
IVD Raw Materials
ORF » Species Summary » Ovis aries » HYAL2 cDNA ORF clone
| Gene Symbol | HYAL2 |
| Entrez Gene ID | 443154 |
| Full Name | hyaluronoglucosaminidase 2 |
| Synonyms | oHyal2 |
| Gene Type | protein-coding |
| Organism | Ovis aries(sheep) |
| mRNA | Protein | Name |
|---|---|---|
| XM_012099237.3 | XP_011954627.1 | hyaluronidase-2 isoform X1 |
| XM_012099238.2 | XP_011954628.1 | hyaluronidase-2 isoform X1 |
| XM_012099237.2 | XP_011954627.1 | hyaluronidase-2 isoform X1 |
| XM_012099238.3 | XP_011954628.1 | hyaluronidase-2 isoform X1 |
| NM_001009754.1 | NP_001009754.1 | hyaluronidase-2 precursor |
| XM_012099239.2 | XP_011954629.1 | hyaluronidase-2 isoform X1 |
Mechanism of cell entry and transformation by enzootic nasal tumor virus.
Dirks C, Duh FM, Rai SK, Lerman MI, Miller AD
Journal of virology76(5)2141-9(2002 Mar)
Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation.
Rai SK, Duh FM, Vigdorovich V, Danilkovitch-Miagkova A, Lerman MI, Miller AD
Proceedings of the National Academy of Sciences of the United States of America98(8)4443-8(2001 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following HYAL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HYAL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | NM_001009754.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1571414400000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF411974.1. ##Evidence-Data-START## Transcript exon combination :: AF411974.1, JX231101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104494974, SAMEA104494976 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001009754.1 |
| CDS | 33..1463 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001009754.1 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | XM_012099237.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1549296000000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040270.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 6, 2019 this sequence version replaced XM_012099237.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011954627.1 |
| CDS | 160..1590 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_012099237.3 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | XM_012099238.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1450195200000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639028.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012099238.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011954628.1 |
| CDS | 90..1520 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_012099238.2 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | XM_012099237.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1450195200000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639028.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012099237.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011954627.1 |
| CDS | 627..2057 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_012099237.2 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | XM_012099238.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1549296000000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040270.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 6, 2019 this sequence version replaced XM_012099238.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011954628.1 |
| CDS | 159..1589 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_012099238.3 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OSm00074 | |
| Clone ID Related Accession (Same CDS sequence) | XM_012099237.3 , XM_012099238.2 , XM_012099237.2 , XM_012099238.3 , NM_001009754.1 , XM_012099239.2 | |
| Accession Version | XM_012099239.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 1450195200000 | |
| Organism | Ovis aries(sheep) | |
| Product | hyaluronidase-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639028.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012099239.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011954629.1 |
| CDS | 239..1669 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_012099239.2 |
1 | ATGTGGACAG GCCTGGGCCC CGCCGTCACA CTGGCCCTGG TGTTGGTGGT GGCATGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mechanism of cell entry and transformation by enzootic nasal tumor virus. |
Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation. |