C21orf91 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	C21orf91
Entrez Gene ID	54149
Full Name	chromosome 21 open reading frame 91
Synonyms	C21orf14,C21orf38,CSSG1,EURL,YG81
General protein information	Preferred Names chromosome 21 open reading frame 91 Names protein EURL homolog cold sore susceptibility gene 1 early undifferentiated retina and lens
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 21 Map Location: 21q21.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100421.1	NP_001093891.1	protein EURL homolog isoform 3
NM_017447.4	NP_059143.3	protein EURL homolog isoform 2
NM_017447.3	NP_059143.3	protein EURL homolog isoform 2
NM_001100420.1	NP_001093890.1	protein EURL homolog isoform 1
NM_001100420.2	NP_001093890.1	protein EURL homolog isoform 1
NM_001100421.2	NP_001093891.1	protein EURL homolog isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	C21orf91	NP_001093890.1
Mus musculus (house mouse)	D16Ertd472e	NP_001239367.1
Danio rerio (zebrafish)	zgc:110006	NP_001018388.1
Pan troglodytes (chimpanzee)	C21H21orf91	XP_001156300.1
Bos taurus (cattle)	C1H21orf91	NP_001032706.1
Rattus norvegicus (Norway rat)	RGD1563888	NP_001101782.1
Gallus gallus (chicken)	C1H21ORF91	NP_990068.1
Xenopus tropicalis (tropical clawed frog)	c21orf91	NP_001123703.1
Macaca mulatta (Rhesus monkey)	C3H21orf91	XP_001106514.1
Canis lupus familiaris (dog)	C31H21orf91	XP_005638832.1

Gene Ontology
Bibliography

Related articles in PubMed

The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome.
Li SS, Qu Z, Haas M, Ngo L, Heo YJ, Kang HJ, Britto JM, Cullen HD, Vanyai HK, Tan SS, Chan-Ling T, Gunnersen JM, Heng JI
Scientific reports629514(2016 07)

C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.
Kriesel JD, Jones BB, Matsunami N, Patel MK, St Pierre CA, Kurt-Jones EA, Finberg RW, Leppert M, Hobbs MR
The Journal of infectious diseases204(11)1654-62(2011 Dec)

Isolation of a novel cDNA enriched in the undifferentiated chick retina and lens.
Godbout R, Andison R, Katyal S, Bisgrove DA
Developmental dynamics : an official publication of the American Association of Anatomists227(3)409-15(2003 Jul)

Cloning of ARE-containing genes by AU-motif-directed display.
Dominguez O, Ashhab Y, Sabater L, Belloso E, Caro P, Pujol-Borrell R
Genomics54(2)278-86(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following C21orf91 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C21orf91 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02353	NM_017447.4 Latest version!	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu30850	NM_001100421.2 Latest version!	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu06086	NM_001100420.2 Latest version!	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5+	$216.30 $309.00
View Old Accession Versions >>
OHu02353	NM_017447.3	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu06086	NM_001100420.1	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu30850	NM_001100421.1	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C21orf91 ( NM_001100420.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093890.1 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06086
Clone ID Related Accession (Same CDS sequence)	NM_001100420.1 , NM_001100420.2
Accession Version	NM_001100420.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506787200000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, DB066982.1, AK023825.1, AL109761.3 and CR749496.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.59820.1, SRR1803611.92758.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGAAG TTTTTGAAGA GTTAACTCAC CAAGTGCAAG AAAAAGATTC TTTGGCCTCA 
CAGCTCCATG TCCGCCACGT TGCCATCGAA CAGCTTCTGA AGAACTGTTC TAAGTTACCA 
TGTCTGCAAG TAGGGCGAAC AGGAATGAAG TCGCACCTAC CCATAAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093890.1
CDS	92..985
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQEVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN

Target ORF information:

RefSeq Version	NM_001100420.1
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100420.1

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGAAG TTTTTGAAGA GTTAACTCAC CAAGTGCAAG AAAAAGATTC TTTGGCCTCA 
CAGCTCCATG TCCGCCACGT TGCCATCGAA CAGCTTCTGA AGAACTGTTC TAAGTTACCA 
TGTCTGCAAG TAGGGCGAAC AGGAATGAAG TCGCACCTAC CCATAAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C21orf91 ( NM_017447.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_059143.3 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02353
Clone ID Related Accession (Same CDS sequence)	NM_017447.4 , NM_017447.3
Accession Version	NM_017447.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, BC015468.2, AL109761.3 and CR749496.1. On May 31, 2019 this sequence version replaced NM_017447.3. Transcript Variant: This variant (2) has an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal aa, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.210441.1, SRR1803611.13964.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151119, SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGTTT TTGAAGAGTT AACTCACCAA GTGCAAGAAA AAGATTCTTT GGCCTCACAG 
CTCCATGTCC GCCACGTTGC CATCGAACAG CTTCTGAAGA ACTGTTCTAA GTTACCATGT 
CTGCAAGTAG GGCGAACAGG AATGAAGTCG CACCTACCCA TAAACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059143.3
CDS	62..952
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN

Target ORF information:

RefSeq Version	NM_017447.4
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017447.4

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGTTT TTGAAGAGTT AACTCACCAA GTGCAAGAAA AAGATTCTTT GGCCTCACAG 
CTCCATGTCC GCCACGTTGC CATCGAACAG CTTCTGAAGA ACTGTTCTAA GTTACCATGT 
CTGCAAGTAG GGCGAACAGG AATGAAGTCG CACCTACCCA TAAACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C21orf91 ( NM_017447.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_059143.3 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02353
Clone ID Related Accession (Same CDS sequence)	NM_017447.4 , NM_017447.3
Accession Version	NM_017447.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530892800000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, BC015468.2, AL109761.3 and CR749496.1. On Aug 2, 2007 this sequence version replaced NM_017447.2. Transcript Variant: This variant (2) has an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal aa, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.229753.1, SRR1803611.13964.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151119, SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGTTT TTGAAGAGTT AACTCACCAA GTGCAAGAAA AAGATTCTTT GGCCTCACAG 
CTCCATGTCC GCCACGTTGC CATCGAACAG CTTCTGAAGA ACTGTTCTAA GTTACCATGT 
CTGCAAGTAG GGCGAACAGG AATGAAGTCG CACCTACCCA TAAACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059143.3
CDS	92..982
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN

Target ORF information:

RefSeq Version	NM_017447.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017447.3

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGTTT TTGAAGAGTT AACTCACCAA GTGCAAGAAA AAGATTCTTT GGCCTCACAG 
CTCCATGTCC GCCACGTTGC CATCGAACAG CTTCTGAAGA ACTGTTCTAA GTTACCATGT 
CTGCAAGTAG GGCGAACAGG AATGAAGTCG CACCTACCCA TAAACAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C21orf91 ( NM_001100421.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093891.1 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu30850
Clone ID Related Accession (Same CDS sequence)	NM_001100421.1 , NM_001100421.2
Accession Version	NM_001100421.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1530892800000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, AF239726.1, AL109761.3 and CR749496.1. Transcript Variant: This variant (3) lacks an exon in the 3' coding region, compared to variant 1. The resulting isoform (3) is C-terminal truncated, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.205644.1, SRR1660803.207249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093891.1
CDS	92..757
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREE

Target ORF information:

RefSeq Version	NM_001100421.1
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100421.1

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C21orf91 ( NM_001100421.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093891.1 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.

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CloneID	OHu30850
Clone ID Related Accession (Same CDS sequence)	NM_001100421.1 , NM_001100421.2
Accession Version	NM_001100421.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1559145600000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, AF239726.1, AL109761.3 and CR749496.1. On May 31, 2019 this sequence version replaced NM_001100421.1. Transcript Variant: This variant (3) lacks an exon in the 3' coding region, compared to variant 1. The resulting isoform (3) is C-terminal truncated, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.205644.1, SRR1660803.207249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093891.1
CDS	62..727
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREE

Target ORF information:

RefSeq Version	NM_001100421.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100421.2

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C21orf91 ( NM_001100420.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093890.1 Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.

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CloneID	OHu06086
Clone ID Related Accession (Same CDS sequence)	NM_001100420.1 , NM_001100420.2
Accession Version	NM_001100420.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1556812800000
Organism	Homo sapiens(human)
Product	protein EURL homolog isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF739854.1, DA215855.1, DB066982.1, AK023825.1, AL109761.3 and CR749496.1. On Nov 22, 2018 this sequence version replaced NM_001100420.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.383068.1, SRR1803611.92758.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000284881.9/ ENSP00000284881.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGAAG TTTTTGAAGA GTTAACTCAC CAAGTGCAAG AAAAAGATTC TTTGGCCTCA 
CAGCTCCATG TCCGCCACGT TGCCATCGAA CAGCTTCTGA AGAACTGTTC TAAGTTACCA 
TGTCTGCAAG TAGGGCGAAC AGGAATGAAG TCGCACCTAC CCATAAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093890.1
CDS	62..955
Translation	MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQEVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN

Target ORF information:

RefSeq Version	NM_001100420.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100420.2

ORF Insert Sequence:

ATGAACGAAG AGGAGCAGTT TGTAAACATT GATTTGAATG ATGACAACAT TTGCAGTGTT 
TGTAAACTGG GAACAGACAA AGAAACACTC TCCTTCTGCC ACATTTGTTT TGAGCTAAAT 
ATTGAGGGGG TACCAAAGTC TGATCTCTTG CACACCAAAT CATTAAGGGG CCATAAAGAC 
TGCTTTGAAA AATACCATTT AATTGCAAAC CAGGGTTGTC CTCGATCTAA GCTTTCAAAA 
AGTACTTATG AAGAAGTTAA AACCATTTTG AGTAAGAAGA TAAACTGGAT TGTGCAGTAT 
GCACAAAATA AGGATCTGGA TTCAGATTCT GAATGTTCTA AAAACCCCCA GCATCATCTG 
TTTAATTTCA GGCATAAGCC AGAAGAAAAA TTACTCCCAC AGTTTGACTC CCAAGTACCA 
AAATATTCTG CAAAATGGAT AGATGGAAGT GCAGGTGGCA TCTCTAACTG TACACAAAGA 
ATTTTGGAGC AGAGGGAAAA TACAGACTTT GGACTTTCTA TGTTACAAGA TTCAGGTGCC 
ACTTTATGTC GTAACAGTGT ATTGTGGCCT CATAGTCACA ACCAGGCACA GAAAAAAGAA 
GAGACAATCT CTAGTCCAGA GGCTAATGTC CAGACCCAGC ATCCACATTA CAGCAGAGAG 
GAATTGAATT CGATGACTCT TGGTGAGGTA GAGCAACTGA ATGCAAAGCT CCTACAGCAA 
ATCCAGGAAG TTTTTGAAGA GTTAACTCAC CAAGTGCAAG AAAAAGATTC TTTGGCCTCA 
CAGCTCCATG TCCGCCACGT TGCCATCGAA CAGCTTCTGA AGAACTGTTC TAAGTTACCA 
TGTCTGCAAG TAGGGCGAAC AGGAATGAAG TCGCACCTAC CCATAAACAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome.
Scientific reports629514(2016 07)
Li SS,Qu Z,Haas M,Ngo L,Heo YJ,Kang HJ,Britto JM,Cullen HD,Vanyai HK,Tan SS,Chan-Ling T,Gunnersen JM,Heng JI

C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.
The Journal of infectious diseases204(11)1654-62(2011 Dec)
Kriesel JD,Jones BB,Matsunami N,Patel MK,St Pierre CA,Kurt-Jones EA,Finberg RW,Leppert M,Hobbs MR

Isolation of a novel cDNA enriched in the undifferentiated chick retina and lens.
Developmental dynamics : an official publication of the American Association of Anatomists227(3)409-15(2003 Jul)
Godbout R,Andison R,Katyal S,Bisgrove DA

Cloning of ARE-containing genes by AU-motif-directed display.
Genomics54(2)278-86(1998 Dec)
Dominguez O,Ashhab Y,Sabater L,Belloso E,Caro P,Pujol-Borrell R

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C21orf91 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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