gmds cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	gmds
Entrez Gene ID	393461
Full Name	GDP-mannose 4,6-dehydratase
Synonyms	dZ84G17.1,si:ch211-231n5.3,srn,twd,zgc:63772
General protein information	Preferred Names GDP-mannose 4,6-dehydratase Names GDP-mannose 4,6 dehydratase towhead
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200489.3	NP_956783.3	GDP-mannose 4,6 dehydratase isoform 2
NM_001102475.2	NP_001095945.1	GDP-mannose 4,6 dehydratase isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GMDS	XP_545311.4
Bos taurus (cattle)	GMDS	NP_001073800.1
Rattus norvegicus (Norway rat)	Gmds	NP_001034695.1
Danio rerio (zebrafish)	gmds	NP_001095945.1
Drosophila melanogaster (fruit fly)	Gmd	NP_608888.2
Arabidopsis thaliana (thale cress)	MUR1	NP_190685.2
Xenopus tropicalis (tropical clawed frog)	gmds	NP_001032330.1
Macaca mulatta (Rhesus monkey)	GMDS	XP_001089757.1
Oryza sativa (rice)	Os06g0137700	NP_001056735.1
Mus musculus (house mouse)	Gmds	NP_666153.1
Gallus gallus (chicken)	GMDS	XP_418977.4
Caenorhabditis elegans (roundworm)	bre-1	NP_001076669.1
Caenorhabditis elegans (roundworm)	gmd-2	NP_493106.1
Arabidopsis thaliana (thale cress)	GMD1	NP_201429.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006783	XP_308963.3
Homo sapiens (human)	GMDS	NP_001491.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bayés À, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 03)

Fatty liver disease induced by perfluorooctane sulfonate: Novel insight from transcriptome analysis.
Fai Tse WK, Li JW, Kwan Tse AC, Chan TF, Hin Ho JC, Sun Wu RS, Chu Wong CK, Lai KP
Chemosphere159166-177(2016 Sep)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber.
Takamiya M, Weger BD, Schindler S, Beil T, Yang L, Armant O, Ferg M, Schlunck G, Reinhard T, Dickmeis T, Rastegar S, Strähle U
PloS one10(2)e0117645(2015)

Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3.
de la Garza G, Schleiffarth JR, Dunnwald M, Mankad A, Weirather JL, Bonde G, Butcher S, Mansour TA, Kousa YA, Fukazawa CF, Houston DW, Manak JR, Schutte BC, Wagner DS, Cornell RA
The Journal of investigative dermatology133(1)68-77(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following gmds gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gmds cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34774	NM_200489.3 Latest version!	Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODa34796	NM_001102475.2 Latest version!	Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

gmds ( NM_200489.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956783.3 Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ODa34774
Clone ID Related Accession (Same CDS sequence)	NM_200489.3
Accession Version	NM_200489.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1134bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548432000000
Organism	Danio rerio(zebrafish)
Product	GDP-mannose 4,6 dehydratase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK686273.1, EH447791.1, EH497761.1 and EH459452.1. On Jun 14, 2012 this sequence version replaced NM_200489.2. Transcript Variant: This variant (2) includes an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 2) is longer but has the same N- and C-termini compared to isoform 1. Sequence note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. ##Evidence-Data-START## Transcript exon combination :: AB290320.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCAGT GTACAGCAAC GACGACTGGT GGCGGTATGA ACGGAGACAG CAAGAGGAAG 
AGGAAAGTGG CTATCATTAC AGGCATAACC GGTCAGGATG GGTCCTACCT GGCAGAGTTG 
CTCTTGGCTA AAGGTTATGA GGTTCACGGT ATCCTCCGCA GGTCCAGTTC TTTTAACACG 
GGTCGGATCG AGCACCTTTA TCATAACCCT CAAACGCACA CAGAAGGAAG CATTGGAGCT 
ACTAAGGATC ACATGAAGTT GCACTATGGA GACTTGACCG ACAGCACGTG CTTGGTGAAG 
ATCATCAATG AAGTCAAACC CACAGAAATC TACAACCTCG GAGCACAGAG CCACGTCAAG 
ATCTCCTTTG ACCTGGCCGA GTACACAGCA GATGTGGACG GGGTTGGAAC CCTTCGGCTG 
CTGGATGCAG TGAAGACCTG CGGTTTAACT GACACCGTCC GCTTCTACCA GGCCTCCACC 
AGCGAGCTCT ATGGGAAAGT ACAGGAAATT CCCCAGAAAG AAACCACGCC ATTTTACCCG 
CGATCGCCTT ATGGTGCTGC TAAGCTCTAT GCATACTGGA TCGTTATAAA CTTCAGGGAA 
GCCTATAACC TCTTTGCTGT GAATGGGATC TTGTTCAATC ATGAGAGTCC TAGAAGAGGT 
TCAAATTTTG TAACTAGAAA GATCAGTCGC TCCGTGGCGA AGATCCACCT CGGGCAGTTG 
GAGTGCTTCA GCCTGGGCAA TTTGGACTCC ATGCGAGACT GGGGTCATGC CAAAGATTAT 
GTGGAGGCGA TGTGGCTGAT GTTGCAGCAG GAGGAGCCTG TGGATTTTGT CATTGCAACC 
GGGGAAGTAC ACAGTGTTCG AGAGTTTGTG GAGAGAGCCT TCAAACACGT GGGCAAAACC 
ATTGTCTGGG AGGGGAAGGA TGAGAAGGAG GTGGGCCGCT GTCAGGAGAC AGGAGTCATT 
CATGTGAGGG TTGATCCGAA ATACTACCGG CCAACTGAAG TGGACTACTT GCAGGGAGAC 
AGTTCCAAAG CCTTTAAGGT TCTAGGCTGG AAACCACGTG TAACATTTGA GGAGCTTGTT 
AAAGAAATGG TGGACGCGGA CATCAAGCTC ATGCAGAACA ACCCAAATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956783.3
CDS	136..1269
Translation	MAQCTATTTGGGMNGDSKRKRKVAIITGITGQDGSYLAELLLAKGYEVHGILRRSSSFNTGRIEHLYHNPQTHTEGSIGATKDHMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLTDTVRFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVINFREAYNLFAVNGILFNHESPRRGSNFVTRKISRSVAKIHLGQLECFSLGNLDSMRDWGHAKDYVEAMWLMLQQEEPVDFVIATGEVHSVREFVERAFKHVGKTIVWEGKDEKEVGRCQETGVIHVRVDPKYYRPTEVDYLQGDSSKAFKVLGWKPRVTFEELVKEMVDADIKLMQNNPNA

Target ORF information:

RefSeq Version	NM_200489.3
Organism	Danio rerio(zebrafish)
Definition	Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200489.3

ORF Insert Sequence:

ATGGCTCAGT GTACAGCAAC GACGACTGGT GGCGGTATGA ACGGAGACAG CAAGAGGAAG 
AGGAAAGTGG CTATCATTAC AGGCATAACC GGTCAGGATG GGTCCTACCT GGCAGAGTTG 
CTCTTGGCTA AAGGTTATGA GGTTCACGGT ATCCTCCGCA GGTCCAGTTC TTTTAACACG 
GGTCGGATCG AGCACCTTTA TCATAACCCT CAAACGCACA CAGAAGGAAG CATTGGAGCT 
ACTAAGGATC ACATGAAGTT GCACTATGGA GACTTGACCG ACAGCACGTG CTTGGTGAAG 
ATCATCAATG AAGTCAAACC CACAGAAATC TACAACCTCG GAGCACAGAG CCACGTCAAG 
ATCTCCTTTG ACCTGGCCGA GTACACAGCA GATGTGGACG GGGTTGGAAC CCTTCGGCTG 
CTGGATGCAG TGAAGACCTG CGGTTTAACT GACACCGTCC GCTTCTACCA GGCCTCCACC 
AGCGAGCTCT ATGGGAAAGT ACAGGAAATT CCCCAGAAAG AAACCACGCC ATTTTACCCG 
CGATCGCCTT ATGGTGCTGC TAAGCTCTAT GCATACTGGA TCGTTATAAA CTTCAGGGAA 
GCCTATAACC TCTTTGCTGT GAATGGGATC TTGTTCAATC ATGAGAGTCC TAGAAGAGGT 
TCAAATTTTG TAACTAGAAA GATCAGTCGC TCCGTGGCGA AGATCCACCT CGGGCAGTTG 
GAGTGCTTCA GCCTGGGCAA TTTGGACTCC ATGCGAGACT GGGGTCATGC CAAAGATTAT 
GTGGAGGCGA TGTGGCTGAT GTTGCAGCAG GAGGAGCCTG TGGATTTTGT CATTGCAACC 
GGGGAAGTAC ACAGTGTTCG AGAGTTTGTG GAGAGAGCCT TCAAACACGT GGGCAAAACC 
ATTGTCTGGG AGGGGAAGGA TGAGAAGGAG GTGGGCCGCT GTCAGGAGAC AGGAGTCATT 
CATGTGAGGG TTGATCCGAA ATACTACCGG CCAACTGAAG TGGACTACTT GCAGGGAGAC 
AGTTCCAAAG CCTTTAAGGT TCTAGGCTGG AAACCACGTG TAACATTTGA GGAGCTTGTT 
AAAGAAATGG TGGACGCGGA CATCAAGCTC ATGCAGAACA ACCCAAATGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

gmds ( NM_001102475.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001095945.1 Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ODa34796
Clone ID Related Accession (Same CDS sequence)	NM_001102475.2
Accession Version	NM_001102475.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1548432000000
Organism	Danio rerio(zebrafish)
Product	GDP-mannose 4,6 dehydratase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CK686273.1, EH445452.1, EH524042.1 and EH459452.1. On Jun 14, 2012 this sequence version replaced NM_001102475.1. Transcript Variant: This variant (1) encodes the shorter protein (isoform 1). Sequence note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. ##Evidence-Data-START## Transcript exon combination :: AB290319.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCAGT GTACAGCAAC GACGACTGGT GGCGGTATGA ACGGAGACAG CAAGAGGAAG 
AGGAAAGTGG CTATCATTAC AGGCATAACC GGTCAGGATG GGTCCTACCT GGCAGAGTTG 
CTCTTGGCTA AAGGTTATGA GGTTCACGGT ATCCTCCGCA GGTCCAGTTC TTTTAACACG 
GGTCGGATCG AGCACCTTTA TCATAACCCT CAAACGCACA CAGAAGGAAA CATGAAGTTG 
CACTATGGAG ACTTGACCGA CAGCACGTGC TTGGTGAAGA TCATCAATGA AGTCAAACCC 
ACAGAAATCT ACAACCTCGG AGCACAGAGC CACGTCAAGA TCTCCTTTGA CCTGGCCGAG 
TACACAGCAG ATGTGGACGG GGTTGGAACC CTTCGGCTGC TGGATGCAGT GAAGACCTGC 
GGTTTAACTG ACACCGTCCG CTTCTACCAG GCCTCCACCA GCGAGCTCTA TGGGAAAGTA 
CAGGAAATTC CCCAGAAAGA AACCACGCCA TTTTACCCGC GATCGCCTTA TGGTGCTGCT 
AAGCTCTATG CATACTGGAT CGTTATAAAC TTCAGGGAAG CCTATAACCT CTTTGCTGTG 
AATGGGATCT TGTTCAATCA TGAGAGTCCT AGAAGAGGTT CAAATTTTGT AACTAGAAAG 
ATCAGTCGCT CCGTGGCGAA GATCCACCTC GGGCAGTTGG AGTGCTTCAG CCTGGGCAAT 
TTGGACTCCA TGCGAGACTG GGGTCATGCC AAAGATTATG TGGAGGCGAT GTGGCTGATG 
TTGCAGCAGG AGGAGCCTGT GGATTTTGTC ATTGCAACCG GGGAAGTACA CAGTGTTCGA 
GAGTTTGTGG AGAGAGCCTT CAAACACGTG GGCAAAACCA TTGTCTGGGA GGGGAAGGAT 
GAGAAGGAGG TGGGCCGCTG TCAGGAGACA GGAGTCATTC ATGTGAGGGT TGATCCGAAA 
TACTACCGGC CAACTGAAGT GGACTACTTG CAGGGAGACA GTTCCAAAGC CTTTAAGGTT 
CTAGGCTGGA AACCACGTGT AACATTTGAG GAGCTTGTTA AAGAAATGGT GGACGCGGAC 
ATCAAGCTCA TGCAGAACAA CCCAAATGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001095945.1
CDS	136..1248
Translation	MAQCTATTTGGGMNGDSKRKRKVAIITGITGQDGSYLAELLLAKGYEVHGILRRSSSFNTGRIEHLYHNPQTHTEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLTDTVRFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVINFREAYNLFAVNGILFNHESPRRGSNFVTRKISRSVAKIHLGQLECFSLGNLDSMRDWGHAKDYVEAMWLMLQQEEPVDFVIATGEVHSVREFVERAFKHVGKTIVWEGKDEKEVGRCQETGVIHVRVDPKYYRPTEVDYLQGDSSKAFKVLGWKPRVTFEELVKEMVDADIKLMQNNPNA

Target ORF information:

RefSeq Version	NM_001102475.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio GDP-mannose 4,6-dehydratase (gmds), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001102475.2

ORF Insert Sequence:

ATGGCTCAGT GTACAGCAAC GACGACTGGT GGCGGTATGA ACGGAGACAG CAAGAGGAAG 
AGGAAAGTGG CTATCATTAC AGGCATAACC GGTCAGGATG GGTCCTACCT GGCAGAGTTG 
CTCTTGGCTA AAGGTTATGA GGTTCACGGT ATCCTCCGCA GGTCCAGTTC TTTTAACACG 
GGTCGGATCG AGCACCTTTA TCATAACCCT CAAACGCACA CAGAAGGAAA CATGAAGTTG 
CACTATGGAG ACTTGACCGA CAGCACGTGC TTGGTGAAGA TCATCAATGA AGTCAAACCC 
ACAGAAATCT ACAACCTCGG AGCACAGAGC CACGTCAAGA TCTCCTTTGA CCTGGCCGAG 
TACACAGCAG ATGTGGACGG GGTTGGAACC CTTCGGCTGC TGGATGCAGT GAAGACCTGC 
GGTTTAACTG ACACCGTCCG CTTCTACCAG GCCTCCACCA GCGAGCTCTA TGGGAAAGTA 
CAGGAAATTC CCCAGAAAGA AACCACGCCA TTTTACCCGC GATCGCCTTA TGGTGCTGCT 
AAGCTCTATG CATACTGGAT CGTTATAAAC TTCAGGGAAG CCTATAACCT CTTTGCTGTG 
AATGGGATCT TGTTCAATCA TGAGAGTCCT AGAAGAGGTT CAAATTTTGT AACTAGAAAG 
ATCAGTCGCT CCGTGGCGAA GATCCACCTC GGGCAGTTGG AGTGCTTCAG CCTGGGCAAT 
TTGGACTCCA TGCGAGACTG GGGTCATGCC AAAGATTATG TGGAGGCGAT GTGGCTGATG 
TTGCAGCAGG AGGAGCCTGT GGATTTTGTC ATTGCAACCG GGGAAGTACA CAGTGTTCGA 
GAGTTTGTGG AGAGAGCCTT CAAACACGTG GGCAAAACCA TTGTCTGGGA GGGGAAGGAT 
GAGAAGGAGG TGGGCCGCTG TCAGGAGACA GGAGTCATTC ATGTGAGGGT TGATCCGAAA 
TACTACCGGC CAACTGAAGT GGACTACTTG CAGGGAGACA GTTCCAAAGC CTTTAAGGTT 
CTAGGCTGGA AACCACGTGT AACATTTGAG GAGCTTGTTA AAGAAATGGT GGACGCGGAC 
ATCAAGCTCA TGCAGAACAA CCCAAATGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 03)
Bayés À,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Fatty liver disease induced by perfluorooctane sulfonate: Novel insight from transcriptome analysis.
Chemosphere159166-177(2016 Sep)
Fai Tse WK,Li JW,Kwan Tse AC,Chan TF,Hin Ho JC,Sun Wu RS,Chu Wong CK,Lai KP

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber.
PloS one10(2)e0117645(2015)
Takamiya M,Weger BD,Schindler S,Beil T,Yang L,Armant O,Ferg M,Schlunck G,Reinhard T,Dickmeis T,Rastegar S,Strähle U

Interferon regulatory factor 6 promotes differentiation of the periderm by activating expression of Grainyhead-like 3.
The Journal of investigative dermatology133(1)68-77(2013 Jan)
de la Garza G,Schleiffarth JR,Dunnwald M,Mankad A,Weirather JL,Bonde G,Butcher S,Mansour TA,Kousa YA,Fukazawa CF,Houston DW,Manak JR,Schutte BC,Wagner DS,Cornell RA

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gmds cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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